Glucagon-like peptide-1 (GLP-1) improves coronary microvascular endothelial function after cardiac arrest and resuscitation and prevents anoxia-induced coronary microvascular endothelial cell death. The FASEB Journal. 2011; 25: 1023.
Glucagon-Like Peptide-1 (GLP-1) is a 30-amino acid peptide primarily produced by endocrine cells in the intestines. As an incretin, GLP-1 regulates food intake and glucose homeostasis via central (e.g., hypothalamus) and peripheral (e.g., pancreas) mechanisms. GLP-1 also acts as a ...
Cardioprotective and Vasodilatory Actions of Glucagon-Like Peptide 1 Receptor Are Mediated Through Both Glucagon-Like Peptide 1 Receptor–Dependent and –Independent Pathways — Data Supplement Background— The failing heart demonstrates a preference for glucose as its metabolic substrate. Whether enhancing ...
initially presented in theWorld Journal of Gastroenterology. We revisit their focus on the role of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in treating metabolic dysfunction-associated fatty liver disease, and supplement their work by exploring the broader systemic applications...
Figure 1. Study Group Selection Flow Diagram View LargeDownload T2D indicates type 2 diabetes. aThe combined total of patients is not necessarily a sum of the individuals from each of the groups because individuals could be prescribed both glucagon-like peptide 1 receptor agonists (GLP-1RAs) and...
The incretin hormone glucagon-like peptide-1 (GLP-1), coencoded and expressed in the proglucagon gene in intestine and endocrine pancreas of all vertebrates, is an important regulator of insulin secretion in the postprandial state of mammals. Additionally, the hormone acts in concert with insulin ...
Two glucagon-like peptide-1 (GLP-1) receptor agonists are currently approved for use in patients with type 2 diabetes mellitus: exenatide and liraglutide. Both of these injectable agents improve glycemic control as monotherapy or as combination therapy w
Slimaglutide® is a groundbreaking weight management supplement utilizing berberine along with 10 other Glucagon-like Peptide-1 (GLP-1) Receptor agonist and secretagogues to provide a natural and effective solution for blood sugar...
Mimetics and analogs that extend the half-life of native glucagon-like peptide-1 (GLP-1), i.e., glucagon-like peptide-1 receptor agonists (GLP-1 RAs), at t
doi:10.1001/jamanetworkopen.2023.14493 Key Points Question Among adults with type 2 diabetes (T2D), what is the efficacy, safety, and tolerability of the novel, orally administered, small molecule glucagon-like peptide 1 receptor agonist danuglipron? Findings In this phase 2 randomized clinical ...