Glucagon-like peptide-1 receptor (GLP1R; GLP-1R); glucagon receptor (GCGR)Science-Business eXchange - Studies in rodents suggest that a coagonist of GLP1R and GCGR could help treat obesity.Science-Business eXchangedoi:10.1038/scibx.2009.1149None
The glucagon-like peptide-1 (GLP-1) receptor, known as GLP-1R, is a vital component of the G protein-coupled receptor (GPCR) family and is found primarily on the surfaces of various cell types within the human body. This receptor specifically interacts with GLP-1, a key hormone that pla...
The glucagon-like peptide-1 receptor (GLP1R) is a member of the glucagon receptor family of G protein-coupled receptors found in the pancreas, heart, blood vessels, gastrointestinal (GI) tract, kidney, lung, breast, and central nervous system [49]. Activation of GLP1R has been...
糖尿病和肥胖症是当今全球性的公共卫生负担,靶向胰高血糖素样肽-1受体(Glucagon-like peptide-1 receptor, GLP-1R)的单靶点和多重激动剂以其显著的降糖及减重疗效一跃成为“明星”药物1。GLP-1R由内源性激素GLP-1(7-36)激活进而控制血糖水平。但它在体内被二肽基肽酶4(Dipeptidyl peptidase-4, DPP-4)迅速降...
葡萄糖依赖性促胰岛素释放多肽受体(Glucose-dependent insulinotropic polypeptide receptor,GIPR)、胰高血糖素样肽-1受体(Glucagon-like peptide-1 receptor,GLP-1R)和胰高血糖素受体(Glucagon receptor,GCGR)是调节糖脂和氨基酸代谢的B1类...
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that promotes healthy insulin signaling, regulates blood sugar levels, and suppresses appetite. Consequently, numerous GLP-1 receptor (GLP-1R) stimulating drugs have been developed and approved by the US Food and Drug Administration (FDA) ...
receptorGlucagon-like peptide-1 receptor agonists (GLP-1RAs) are gaining ground as therapeutic modalities in combination with insulin in patients with type 2 diabetes mellitus. Exploiting the multiple benefits of incretin-based therapies in certain patient populations, especially in those who would ...
胰高血糖素样肽-1(Glucagon-likepeptide-1,GLP-1)是一种内源性肠促胰岛素激素,由31个氨基酸残基组成,由胰高血糖素原基因转录、翻译及加工而成。GLP-1具有葡萄糖浓度依赖性降糖作用,其受体激动剂(GLP-1RA)能够模拟GLP-1的生理作用,是降糖和减重药物研发的热门靶点。
英文名称：Glucagon - like peptide - 1 (GLP - 1)(7 - 36), amide acetate；Human GLP - 1 (7 - 36), amide acetate 中文名称：胰高血糖素样肽 - 1 (7 - 36) 酰胺醋酸盐 氨基酸序列：His - Ala - Glu - Gly - Thr - Phe - Thr - Ser - Asp - Val - Ser - Ser - Tyr - Leu - ...
Recombinant Glucagon Like Peptide 1 Receptor (GLP1R) information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices, suppliers, SDS and more, available at Chemicalbook.