GLTSCR1在结直肠癌中调节ZO1可变剪接的模式图 张红河课题组长期从事结直肠癌转移机制研究。在前期工作中报道了GLTSCR1通过与BRD4结合形成复合物抑制癌基因的转录延伸,从而抑制了结直肠癌的转移。在此次研究中该课题组发现,GLTSCR1通过结合ZO1启动子序列抑制RNA 聚合酶 II在ZO1基因上的转录延伸,使ZO1 E23弱剪接位点有...
GLTSCR1 导读 基因简介 中英文全称:神经胶质瘤肿瘤抑制因子候选区基因1 glioma tumor suppressor candidate region gene 1 OMIM/位置:605690 19q13.3
Through binding to bromodomains and the phosphorylation‐dependent interaction domain of bromodomain protein 4 (BRD4) via the C‐terminus, GLTSCR1 blocks oncogenic transcriptional elongation. However, truncated GLTSCR1 translocates into the cytoplasm and loses BRD4 binding domain, which induces the ...
(GLTSCR1 antisense RNA 1) 基因基本信息 基因简称(symbol) GLTSCR1-AS1 [HGNC] [GeneCards] [NCBI] 基因种类(locus group) non-coding RNA 同源简称(alias symbol) 基因家族代码(gene_family_id) [HGNC] [GenScript] omim代码 entrez码 0 [Vega] ensembl基因码 ENSG00000269806 [Ensembl] 基因...
Anti-GLTSCR1 antibody produced in rabbit Anti-glioma tumor suppressor candidate region gene 1 基本信息 Human Protein Atlas Number【人类蛋白质图谱编号】 HPA056211 Human Protein Atlas characterization data Immunogen【免疫原】 glioma tumor suppressor candidate region gene 1 recombinant protein epitope signatur...
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Cancer stem cells (CSCs) typically reside in perivascular niches, but whether endothelial cells of blood vessels influence the stemness of cancer cells remains poorly understood. This study revealed that endothelial cell-specific GLTSCR1 deletion promote
产品名称: SureFISH 19q13.33 GLTSCR1-GLTSCR2 RD6 .0 订购此产品 供应商: Agilent 规格: *** 目录价: 19316.7108433735 库存状态: CAS编号: 应用范围: 种属来源: 相关信息: 保存条件: 说明书地址: 点击查看详细 打印此页 关闭此页 上一个:SureFISH 19q13.33 GLTSCR1-GLTSCR2 GR6[G200281G...
本发明公开了一种GLTSCR1前列腺癌预后检测试剂及其试剂盒,其试剂组成如下(20人份):HO1ml,非免疫羊血清工作液1ml,一抗:兔源抗GLTSCR1多克隆抗体10μl,二抗:生物素标记的羊抗兔的IgG工作液1ml,链霉菌抗生物素过氧化物酶溶液1ml,DAB显色剂23ml.本GLTSCR1前列腺癌预后检测试剂盒,包含检测GLTSCR1检测试剂.本...
We termed this complex GBAF because it incorporates two mutually exclusive paralogs, GLTSCR1 (glioma tumor suppressor candidate region gene 1) or GLTSCR1L (GLTSCR1-like), instead of an ARID protein. In addition to GLTSCR1 or GLTSCR1L, the GBAF complex contains BRD9 (bromodomain-containing...