[10]. Rakipovski G, Rolin B, Nøhr J, et al. The GLP-1 Analogs Liraglutide and Semaglutide Reduce Atherosclerosis inApoE-/- and LDLr-/- Mice by a Mechanism That Includes Inflammatory Pathways. JACC Basic Transl Sci. 2018 ...
[7]. Rakipovski G, Rolin B, Nøhr J, et al. The GLP-1 Analogs Liraglutide and Semaglutide Reduce Atherosclerosis inApoE-/- and LDLr-/- Mice by a Mechanism That Includes Inflammatory Pathways. JACC Basic Transl Sci. 2018 Nov 21;3(6):844-857. [8]. Yue W, Li Y, Ou D, et al...
这意味着GLP-1对胰高血糖素分泌的抑制并不完全依赖于生长抑素,GLP-1对胰高血糖素分泌的影响还可以通过forskolin诱导的cAMP变化来模拟。用低浓度forskolin(1~10 nM)处理离体小鼠胰岛可抑制高达60%的胰高血糖素分泌,而高浓度forskolin(0.1~10 μM)...
[9] Meier, J.J., Butler, A.E., Saisho, Y., Monchamp, T., Galasso, R., Bhushan, A., et al. 2008. Beta-cell replication is the primary mechanism subserving the postnatal expansion of betacell mass in humans. Diabetes 57:1584-1594. [10] Chen, H., Gu, X., Liu, Y., Wang,...
[9] Meier, J.J., Butler, A.E., Saisho, Y., Monchamp, T., Galasso, R., Bhushan, A., et al. 2008. Beta-cell replication is the primary mechanism subserving the postnatal expansion of betacell mass in humans. Diabetes 57:1584-1594. ...
4.The mechanism and efficacy of GLP-1 receptor agonists in the treatment of Alzheimer’s disease 5.12-month neurological and psychiatric outcomes of semaglutide use for type 2 diabetes: a propensity-score matched cohort study 6.https://aaic.alz.org/releases-2024/glp-drug-liraglutide-may-protect-...
further identified an intricate interplay between DMHGLP-1R neurons and arcuate NPY/AgRP neurons (ARCNPY/AgRP), to regulate food intake. Our findings reveal a hypothalamic mechanism through which GLP-1RAs control preingestive satiation, offering novel neural targets for obesity and metabolic diseases...
GLP-1RA的作用机制与临床获益 GLP-1RA的作用机制 GLP⁃1RA 通过激活 GLP⁃1 受体以葡萄糖浓度依赖...
[1] Haiyang Du, 1Xiaoyu Meng, Yu Yao, and Jun Xu. The mechanism and efficacy of GLP-1 ...
关键词:胰高糖素样肽 -1 类似物;三磷酸腺苷;环磷酸腺苷;腺苷酸环化酶;胰岛素中国分类号:R58 文献标识码:AMechanism of GLP-1 analogue on glucose-dependenthypoglycemic effectCHEN Han-bei, LIN Ning, SU Qing(Department of Endocrinology, Xinhua Hospital, Shanghai Jiaotong University,Shanghai 200092, P....