I.L., Woods, S.C., et al. 1998.Central infusion of glucagon-like peptide-1-(7-36) amide (GLP-1) receptor antagonistattenuates lithium chloride-induced c-Fos induction in rat brainstem. Brain Res 801:164-170.
1 周 1 次的给药频率极大地提高了患者的依从性,改善了糖友们的生存质量和预后,为广大糖尿病人群开启了新的治疗篇章。 文字| 吕颖奇 排版| 杨婷、刘得辰 图片| 部分来源网络(侵删) 审核| 魏琼 参考文献 [1] Waser B, Reubi J C. Radiolabelled GLP...
参考资料: [1] Amylyx Pharmaceuticals Announces Acquisition of Phase 3-ready GLP-1 Receptor Antagonist (Avexitide) with FDA Breakthrough Therapy Designation. Retrieved July 10, 2024, from https://www.amylyx.com/news/amylyx-pharmaceuticals-announces-acquisition-of-phase-3-ready-glp-1-receptor-antago...
I.L., Woods, S.C., et al. 1998. Central infusion of glucagon-like peptide-1-(7-36) amide (GLP-1) receptor antagonist attenuates lithium chloride-induced c-Fos induction in rat brainstem. Brain Res 801:164-170.
[1] Pettus J, Boeder SC, Christiansen MP, et al. Glucagon receptor antagonist volagidemab in type 1 diabetes: a 12-week, randomized, double-blind, phase 2 trial. Nat Med, 2022, 28(10):2092-2099. [2] Cui X, Feng J, Wei ...
[1] Amylyx Pharmaceuticals Announces Acquisition of Phase 3-ready GLP-1 Receptor Antagonist (Avexitide) with FDA Breakthrough Therapy Designation. Retrieved July 10, 2024, from https://www.amylyx.com/news/amylyx-pharmaceuticals-announces-acquisition-of-phase-3-ready-glp-1-receptor-antagonist-avexit...
了解GLP-1影响体重的相关机制。 自胰高糖素样肽-1(GLP-1)被发现以来,已然成为一种“多面手”激素——其接二连三的代谢功能被人们发现,远远超出了作为肠促胰素的经典定义。GLP-1众多有益的作用使其受体激动剂逐渐成为更多新兴的治疗领域如脂肪肝、肥胖和神经退行性疾病等的冉冉之“星”药物,而GLP-1的减重作用...
产品名:Exendin (9-39) amide,GLP-1受体拮抗剂;Exendin Fragment 9-39, GLP-1 receptor antagonist;Exendin Fragment 9-39 CAS号:133514-43-9 结构式:Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 ...
产品名:Exendin (9-39) amide,GLP-1受体拮抗剂;Exendin Fragment 9-39, GLP-1 receptor antagonist;Exendin Fragment 9-39 CAS号:133514-43-9 结构式:Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 ...
产品名:Exendin (9-39) amide,GLP-1受体拮抗剂;Exendin Fragment 9-39, GLP-1 receptor antagonist;Exendin Fragment 9-39 CAS号:133514-43-9 结构式:Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 ...