Glucagon Like Peptide 1 (GLP-1) mimetic drugs or degradation inhibitors mimic the action of native GLP-1 as a incretin hormone and have become a common second line of therapy for Type 2 diabetes. However, an important clinical issue is whether these drugs increase the incidence of pancreatitis...
Differences between GLP-1 receptor agonists and DPP-4 inhibitors[1] Service: CMC Research of GLP-1 Medicilon can provide API process development and preparation R&D services for GLP-1 drugs. Medicilon has established a platform for the development of cGMP APIs and has developed GMP APIs for clin...
[1] Liakos, C. I. et al. Blood pressure-lowering effect of newer antihyperglycemic agents (SGLT-2 inhibitors, GLP-1 receptor agonists, and DPP-4 inhibitors. Am J Cardiovasc Drugs. 2021, 21, 123-137. [2] Nauck, M. A....
Targeting the incretin system has become an important therapeutic approach for treating type 2 diabetes. Two drug classes have been developed: glucagon-like peptide (GLP)-1 receptor agonists and dipeptidyl peptidase 4 (DPP-4) inhibitors. Clinical data have revealed that these therapies improve glycemi...
Glucagon Like Peptide 1 (GLP-1) mimetic drugs or degradation inhibitors mimic the action of native GLP-1 as a incretin hormone and have become a common second line of therapy for Type 2 diabetes. However, an important clinical issue is whether these drugs increase the incidence of pancreatitis...
dipeptidyl peptidase-4 (DPP-4) inhibitors, and SGLT2 inhibitors — as controls. They also had a group of more than a million people who didn’t start taking any new drugs. If you’re keeping track, that’s actually four distinct control groups. I’ll try to integrate the results for ...
[4] Ueda P, Wintzell V, Melbye M, et al. Use of DPP4 Inhibitors and GLP-1 Receptor Agonists and Risk of Intestinal Obstruction: Scandinavian Cohort Study. Clin Gastroenterol Hepatol. 2024 Jun;22(6):1226-1237. [...
In this review, the reno-protection and their mechanisms of new types of anti-drugs such as DPP-4 inhibitors, GLP-1 receptor agonists and SGLT-2 ... 叶山东 - 《China Tropical Medicine》 被引量: 0发表: 2020年 胰岛素和GLP-1类似物长效化策略研究的最新进展 胰岛素类似物和胰高血糖素样肽-1...
Few studies explored the effect of the combination of glucose sodium-cotransporter-2 inhibitors (SGLT-2i) and glucagon-like peptide-1 receptor agonists (GLP-1RA) on the incidence of cardiovascular events in patients with type 2 diabetes (T2D) and acute myocardial infarction (AMI). Methods We re...
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