2023年8月，《Frontiers in Endocrinology》杂志发表的一篇题为《Comparison of the efficacy and safety of 10 glucagon-like peptide-1 receptor agonists as add-on to metformin in patients with type 2 diabetes: a systematic review》的综述填补了空白。作者比较了10种胰高血糖素样肽-1受体激动剂（GLP-1RA...
2023年8月,《Frontiers in Endocrinology》杂志发表的一篇题为《Comparison of the efficacy and safety of 10 glucagon-like peptide-1 receptor agonists as add-on to metformin in patients with type 2 diabetes: a systematic review》的...
2023年8月,《Frontiers in Endocrinology》杂志发表的一篇题为《Comparison of the efficacy and safety of 10 glucagon-like peptide-1 receptor agonists as add-on to metformin in patients with type 2 diabetes: a systematic review》的综述填补了空白。作者比较了10种胰高血糖素样肽-1受体激动剂(GLP-1RA)...
9.NikfarS, Abdollahi M, Salari P. The efficacy and tolerability of exenatidein comparison to placebo; a systematic review and meta-analysis ofrandomized clinical trials. J Pharm Pharm Sci. 2012;15:1-30. 10.LilyL Wu, Chiuan Chian Chiou, Pi Yueh Chang,et al., Urinary 8-OHdG: amarker of...
Comparison of the Efficacy and Pharmacoeconomics of GLP-1 Analogues and Insulin Glargine Combined with Metformin Hydrochloride in the Treatment of Type 2 Diabetes Mellitus REN Qinghua The First Affiliated Hospital of Zhengzhou University, Zhengzhou Henan 450002, China.[Abstract] Objective: To compare the...
一 ,GLP-1 受体激动剂发展史及分类 肠促胰 素 (Incretin)是从肠道分泌的可刺激胰 岛素 分泌的物质的统称.1964 年,Elrick 等发[5] 现 "肠促胰素效应 ",即在相同的血糖变化水平下 ,与静 脉注射葡萄糖 相比,口服葡萄糖可引起更多的胰岛 在保留其与 GLP-1 受体结合并发挥生物学效应的 同时使 其不易被 ...
艾塞那肽 (短效) 和 利司那肽会延缓胃排空,不能用于重度胃肠道疾病(如胃轻瘫)患者。重度胃轻瘫患者应慎用长效 GLP-1 受体激动剂 (利拉鲁肽、度拉糖肽、一周 1 次艾塞那肽、司美格鲁肽)。 对该类产品活性成分或任何其他辅料过敏者。 六 肾功能损害者适合哪种 GLP-1RA?
本期特邀解放军总医院李春霖教授带您了解降糖药物GLP-1对下丘脑-垂体-肾上腺轴、对学习/记忆和神经保护以及对骨骼的影响。
[4] Rowland, N.E., Crews, E.C., Gentry, R.M. 1997. Comparison of Fos induced in rat brain by GLP-1 and amylin. Regul Pept 71:171-174. [5] Gil-Lozano, M., Perez-Tilve, D., Alvarez-Crespo, M., Martis, A., Fernandez, A.M., Catalina, P.A., et al. 2010. GLP-1(7...
11.Htike ZZ, Zaccardi F, Papamargaritis D,et al,Efficacy and safety of glucagon-like peptide-1 receptor agonists in type 2 diabetes: A systematic review and mixed-treatment comparison analysis.Diabetes Obes Metab....