GLP-1这个蛋白就比较神奇,它的全称叫"胰高血糖素样肽-1",是一种肠道中产生的激素,能够在高血糖时刺激胰岛素大量分泌,注意是在"高血糖"的时候,所以就比单纯注射胰岛素好了很多,因为当血糖下降到正常水平后再激活GLP-1的受体也不会继续增加胰岛素的分泌了,就不会引起低血糖。人们自然就想用这个性质开发能够激活GLP...
Mireya, a 32-year-old from Austin, Texas, has experienced some typical side effects, such as nausea and constipation, since she began taking a GLP-1 in March 2024. But the biggest challenge by far has been changing her relationship with food. “We recently vacationed, and I wanted to eat...
For Constipation – I’ve found that adding a daily docusate regimen has significantly helped me stay regular. There were times in the first couple of weeks when I needed more aggressive help and got some over-the-counter laxatives. The dietary recommendations above are likely the most helpful...
“Most of the GLP-1 medications are intended for long-term use with people who have diabetes or pre-diabetes,” explains Dr. Russo. “Once you reach your weight loss goal, you can go to a maintenance level. But like anything else, once you stop the diet or stop themedicationsand start...
As the researchers noted, prior studies have suggested that people taking GLP-1`medications might face a higher odds of "aspirating" food when undergoing procedures requiring anesthesia. Because thedrugscan also causeconstipationand a delayed emptying of the stomach, Mathur's group wondered if the ...
The most common include nausea, vomiting, diarrhea, abdominal pain, and constipation. A few more serious side effects, like pancreatitis and thyroid C-cell tumors, did appear in some trials, but more testing is needed.1 If you start taking a semaglutide (GLP-1 RA), you’ll also need to...
(namely nausea and vomiting, constipation and abdominal pain). These symptoms usually occur only during the initial period when semaglutide is escalated to the target dose. A common effect of GLP-1 receptor agonists is decreased appetite, the primary mechanism for their effectiveness in weight loss...
Themost common side effectsfrom GLP-1 agonists (like Ozempic) are nausea, constipation, vomiting, diarrhea and loss of muscle mass. It can also cause swelling, shortness of breath, thyroid tumors in mice and cause inflammation of the kidney, gallbladder, pancreas, and eyes. ...
“The other side effects, nausea, diarrhea, decreased appetite, vomiting, constipation, and ulcers — those all can then impact [patients’] day-to-day life and ability to live a healthy life or do the things that are important to [them],” Bhatt noted. ...
Constipation was also recorded in ~7% of participants treated with liraglutide, ~11% of patients treated with long-acting exendin-4 and ~ 6% of patients treated with exendin-4 [91,93]. Given these relatively common adverse effects in the GI tract, GLP-1 would have to be prescribed with ...