There are several other types ofdiabetes medications, like oral (taken by mouth) medications. One type oforalmedication,metformin, is the go-to medication for treating T2D. But your healthcare provider may recommend a GLP-1 agonist if: oral :口服的 metformin:二甲双胍 go-to:首选 Metformin isn...
GLP-1R agonists Exenatide, Lixisenatide, Liraglutide, Dulaglutide, and Albiglutide have been approved for the treatment of type 2 diabetes. This article will review GLP-1R agonist mechanism of action, biology, safety profile of various GLP-1R agonists, and their structure–activity relationships.A. ...
like pancreatitis or anaphylaxis, are rare. Before starting any GLP-1 agonist, discuss the medication's risks, including allergic reactions, pregnancy contraindications, and potential complications. Regular appointments with healthcare providers are necessary for monitoring the treatment's effecti...
but there’s off-label use of these agents in people with type 1 diabetes for managing weight. One study presented at the meeting found that 18% of young people with type 1 diabetes who had severe obesity and 34%...
[2] Nauck, M. A., & D'Alessio, D. A. (2022). Tirzepatide, a dual GIP/GLP-1 receptor co-agonist for the treatment of type 2 diabetes with unmatched effectiveness regrading glycaemic control and body weight reduction. Cardiovascular diabetology, 21(1), 169.https://doi.org/10.1186/s129...
[20] McCarty, D., Coleman, M., Boland, C.L. 2017. Lixisenatide: A New Daily GLP-1 Agonist for Type 2 Diabetes Management. Ann Pharmacother 51:401-409. [21] Finan, B., Clemmensen, C., Muller, T.D. 2015. Emerging opportunities ...
GLP-1 Receptor Agonist and SGLT2 Inhibitor Prescribing in People With Type 1 Diabetes Piaopiao Li, MS1,2; Zhiyan Li, MPH1; Elizabeth Staton, BA3; et al Guillermo E. Umpierrez, MD4; Georgia Davis, MD4; Hui Shao, MD, PhD1,5; Francisco J. Pasquel, MD, MPH1,4 Author ...
Pathways to Sustainable GLP-1 Receptor Agonist Off-Ramping Shaminie J. Athinarayanan, PhD; Caroline G. P. Roberts, MD JAMA Internal Medicine FullText As of 2024, more than 1 billion people are estimated to be living with obesity worldwide.1The glucagon-like peptide-1 ...
INTRODUCTION: GLP-1 receptor agonists have been shown to be effective in the treatment of type 2 diabetes mellitus (T2DM). Although the first GLP-1 receptor agonist, exenatide, was approved in the mid-2000s, other agents with longer durations of action (that do not require twice-daily dosing...
[26] Palanca, Ana, et al. "Real-World Evaluation of GLP-1 Receptor Agonist Therapy Persistence, Adherence and Therapeutic Inertia Among Obese Adults with Type 2 Diabetes." Diabetes Therapy 14.4 (2023): 723-736.[27] Luli, Alex, et al. "Barriers to Obtaining GLP-1 Receptor Agonists and ...