2. Frias, J. P., Nauck, M. A., Van, J., Kutner, M. E., Cui, X., Benson, C., Urva, S., Gimeno, R. E., Milicevic, Z., Robins, D., and Haupt, A. (2018) Efficacy and safety of LY3298176, a novel dual GIP and GLP-1
GLP-1Glucagon-like peptide 1Type 1 diabetesDespite years of research in the field of type 1 diabetes, patients with the disease remain without a therapeutic agent that can alter the underlying immune response in a clinically beneficial way. Glucagon-like peptide 1 agonist therapies have shown ...
Patients taking GLP-1 drugs also had a 31% lower risk of dying within five years of starting on the medication, researchers said. “Our study results are the strongest evidence to date that GLP-1 agonist drugs are largely safe and effective tools for addressing type 2 diabetes in kidney tra...
对于一些肠胃肠道较为脆弱的人群来说,还是应当对GLP-1药物敬而远之。 不过,尽管有这些副作用,但仍是瑕不掩瑜的,围绕GLP-1药物对疾病的治疗研究也越来越多。我们也期待,未来GLP-1药物能够在更多领域发光发热。 参考资料 1.Obesity drugs have ano...
Recent research indicates that drugs targeting incretin may help reduce inflammation and blood clotting in sepsis by activating the GLP-1 receptor24. In our study, over 50% of patients had sepsis could support findings that GLP-1 RAs could lower the risk of death from sepsis25. Moreover, we...
agonist:激动剂 mimick:模仿 hormone:激素 The researchers found that people with diabetes who started taking most versions of GLP-1 agonists were between 11% and 65% less likely to be newly diagnosed with depression than people with diabetes who didn't take one of the drugs. The greatest reduct...
对于一些肠胃肠道较为脆弱的人群来说,还是应当对GLP-1药物敬而远之。 不过,尽管有这些副作用,但仍是瑕不掩瑜的,围绕GLP-1药物对疾病的治疗研究也越来越多。我们也期待,未来GLP-1药物能够在更多领域发光发热。 参考资料 1.Obesity drugs have another superpower: taming inflammation.Nature. ...
耀海生物基于多年的微生物表达体系（大肠杆菌、酵母）CDMO服务经验，具备GMP级别重组GLP-1类似物的生产服务能力：生产周期短、产品质量达标，可以满足产品注册申报的需求，以期成为众多生物企业在GLP-1类似物赛道的助跑员！参考文献 [1] Dhillon S. Semaglutide: First Global Approval. Drugs. 2018 Feb;78(2):275-...
From Alzheimer's disease to depression to heart disease, Ozempic and other GLP-1 agonist drugs appear to offer a solution. Can one type of drug really tackle so many conditions, and if so, how does it actually work? There were downsides for the people taking GLP-1 drugs, howeve...
In new revelations about glucagon-like peptide-1 (GLP-1) drugs like Ozempic, a study has demonstrated the therapies could protect against dementia. In a Phase IIb trial, Novo Nordisk’s GLP-1 receptor agonist liraglutide appears to reduce shrinking in the parts of the brain that control memory...