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[44] Bjerre Knudsen, L., Madsen, L.W., Andersen, S., Almholt, K., de Boer, A.S., Drucker, D.J., et al. 2010. Glucagon-like Peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cel...
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[52] Franklin, I., Gromada, J., Gjinovci, A., Theander, S., Wollheim, C.B. 2005. Beta-cell secretory products activate alpha-cell ATP-dependent potassium channels to inhibit glucagon release. Diabetes 54:1808-1815. [53] Zho...
[52] Franklin, I., Gromada, J., Gjinovci, A., Theander, S., Wollheim, C.B. 2005. Beta-cell secretory products activate alpha-cell ATP-dependent potassium channels to inhibit glucagon release. Diabetes 54:1808-1815. [53] Zhou, H., Zhang, T., Harmon, J.S., Bryan, J., Robertson...
PCSK1:激素前转化酶1/3;PCSK2:激素前转化酶2;NTS:孤束核;GRPP:肠高血糖素相关肽;IP-1:中间肽-1;IP-2:中间肽-2;MPGF:主要胰高血糖素原片段;GLP-1:胰高糖素样肽-1;GLP-2:胰高糖素样肽-2。 02 GLP-1刺激胰岛素分泌和合成的分子机制
1. Breton J, Tennoune N, Lucas N, Francois M, Legrand R, Jacquemot J, Goichon A, Guérin C, Peltier J, Pestel-Caron M. Gut commensal E. coli proteins activate host satiety pathways following nutrient-induced bacterial growth. Cell Metab. 2016;23(2):324–334. doi: 10.1016/j.cmet.20...
利拉鲁肽的这些优势为2型糖尿病患者的临床治疗提供了新的理想选择.%Glucagon-like peptide 1 (GLP-1) receptor agonists and dipeptidyl peptidase-4 (DPP-4)inhibitors are two classes of incretin-based drugs for type 2 diabetes treatment.GLP-1 receptor agonists can directly activate the GLP-1 ...
Walk After Meals –A 10-30 minute walk post-meal boosts GLP-1 and reduces blood sugar spikes. Morning Sunlight Exposure –Get 10-20 minutes of sunlight to regulate hunger hormones and reduce stress. Cold Therapy –Try cold showers (30-60 seconds) or ice baths to activate brown fat and bo...
[32] Kawasaki H, Springett GM, Mochizuki N, Toki S, Nakaya M, Matsuda M,et al, 1998. A family of cAMP-binding proteins that directly activate Rap1. Science 282:2275-2279. [33] Doyle ME, Egan J M,2007. Mechanisms of action...