Objective and requirement(1)After learning this chapter, students should have a good mastery of thestructure and function of myoglobin and hemoglobin; allosteric effects; Bohr effects; effect of 2,3-BPG on oxygen affinity; (2)After learning this chapter, students shoul 2、d have a fair ...
This chapter provides an overview of structure-function relations of industrially relevant globular proteins of animal and plant sources. The various globular proteins vary in amino acid composition, which is of importance for nutritional value. The presence of protease inhibitors co-fractionated with ...
Structure and Function of the Acidic Ribosomal Stalk Proteins. The acidic L7 / L12 (prokaryotes) and P1 / P2 (eukaryotes) proteins are the only ribosomal components that occur in more than one, specifically four, copie... Wahl,C Markus,Möller,... - 《Current Protein & Peptide Science》...
Determining function of a protein from its primary structure is among the most important problems in molecular biology. The usual approach – inferring function from homology – requires detailed description of functional units, considerable amount of data and is computationally rather demanding. Instead,...
Since for the two examples analysed here we managed to introduce residues reducing protein aggregation while conserving both protein structure and function one might wonder why these solutions have not been explored naturally. Of course, the concentration at which these proteins naturally occur may be ...
1.any of numerous organic molecules constituting a large portion of the mass of every life form, composed of 20 or more amino acids linked in one or more long chains, the final shape and other properties of each protein being determined by the side chains of the amino acids and their chem...
Proteins: Structure, Function, and Bioinformatics Volume 55, Issue 4, pages 1014–1022, 1 June 2004Additional Information How to Cite Trovato, A. and Seno, F. (2004), A new perspective on analysis of helix–helix packing preferences in globular proteins. Proteins, 55: 1014–1022. doi: 10.1...
Applying the model to a range of proteins which vary in terms of structure and function reveals globally accordant structures and locally discordant fragments which disrupt the hydrophobic core and appear to mediate the protein's biological function. Solenoids provide an example of structural elements ...
crystalline proteins that are easily soluble in water or weak saline solutions; their molecules are close to spherical (the ratio of the sphere’s axes does not exceed 5). Such a molecular structure is determined by the spiralization of the peptide chain and by its dense packing, which is ...
The task of assigning a function to each new protein structure resulting from high-throughput structural genomics experiments requires reliable computational annotation methods. Identified functionally important amino acids can provide preliminary clues on the co-evolution and molecular workings of proteins. ...