In vitro, the elimination of the histone H3 N-terminal peptide containing lysine 9 by trypsin blocked chromatin self-association by MENT, while reconstitution with dimethylated but not acetylated N-terminal domain of histone H3 specifically restored chromatin self-association by MENT. We suggest that...
Structure and properties of a bis-histidyl ligated globin from Caenorhabditis elegans. Globins are heme-containing proteins that are best known for their roles in oxygen (O(2)) transport and storage. However, more diverse roles of globins in ... Jungjoo Yoon, Mark A. Herzik, Jr., ...
coli requires coexpression with calmodulin, therefore, a plasmid containing human Calmodulin was co-transfected as previously reported for mouse iNOS expression61. The purified protein did show spectral properties consistent with the presence of heme and flavins, nevertheless it did not produce the ...
1 Derivation of HUDEP-2 cells containing a single γ-globin gene. Genome browser view of deletions introduced into HUDEP-2 cells to generate the HUDEP-2Δεγδβ/GγΑγ line, which contains a single γ-globin gene. The region of the β-like globin gene cluster that was deleted on ...
Prediction programs identify Y75B7AL.1 as a chimeric protein consisting of a G-coupled receptor domain containing 7 transmembrane helices and a globin domain. Its structural properties suggest that this protein may act as an oxygen sensor. The oxygen dependent expression of this globin is ...
特别提示:包括重组小鼠Uteroglobin在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途! 产品名称:重组小鼠Uteroglobin 英文名称:Recombinant Murine Uteroglobin 产品货号:GS4758 产品规格:10μg 分子量:Approximately 16.7kDa,a disulfide-linked homodimeric protein containing two 75 amino acid ...
The red cells that are brightly stained are HbF-containing red cells that appear in heterocellular manner at 6 weeks of life. This test can detect red cells containing a large amount of HbF (usually >50%) that is typical of a fetal red cell, however, it lacks sensitivity in ...
In AEV-cells, a globin-containing RNA of about 33 kb in length is found. This giant RNA seems to be a "Full Domain Transcript" (FDT) transcribed from a LCR [155] (or MRE [105,203]) placed 25kbp upstream of the genes [180]. It is absent in non-erythroid cells but present in...
The expression of the mutant alpha globin protein was observed in immunoprecipitate from lysed RBCs, in which an approximate 400 Da peak shift (corresponding to the loss of four amino acids from the polypeptide chain) was observed in a matrix-assisted laser desorption ionization mass spectrometer...
LDB1 (LIM domain-binding protein 1)/GATA-1 (Gata binding protein 1)/LMO2 (LIM domain only 2) protein complex directly bind to locus control region (LCR) and regulate transcription of globin genes4,5,6. LMO2, a non-DNA binding protein acts as a bridging protein for LDB1, GATA1 and ...