Global Run-On sequencing (GRO-seq) is one of the most sensitive techniques to detect nascent transcription from RNA polymerase (Pol) at a genome-wide level. The protocol incorporates labeled ribonucleotides into
the CSR-1 pathway has been shown to activate the expression of some genes. To evaluate the genome-wide effects of the CSR-1 pathway on Pol II transcription, the authors used a global run-on sequencing (GRO–seq) method that enables mapping of the...
TDA was performed using the AyasdiAI machine intelligence platform (Symphony AyasdiAI, Palo Alto, CA, USA) on the normalized RNA sequencing data, employing a correlation metric combined with two proprietary neighborhood lenses. Groups of patients with similar gene expression profiles were defined ...
TDA was performed using the AyasdiAI machine intelligence platform (Symphony AyasdiAI, Palo Alto, CA, USA) on the normalized RNA sequencing data, employing a correlation metric combined with two proprietary neighborhood lenses. Groups of patients with similar gene expression profiles were defined ...
CloudSeq provides cloud-based bioinformatics and next-generation sequencing services. Its proprietary bio-data analysis platform hosts bioinformatics and sequencing solutions that makes projects easy to run and manage, without the need for expensive instruments or computer hardware. ...
Additionally, certain metadata features, such as those related to sequencing and quality control, were added after initial sample collection. To collate various metadata sources, we built a publicly available repository on Pangea (https://pngb.io/metasub-2021) which assembled a large master ...
These potato whole- genome sequencing projects have also contributed to the significant rise in potato transcriptome studies and reported spatiotemporal changes occurring in various potato tissues using RNA-seq (e.g., Massa et al. 2011; Chandrasekar et al. 2022; Tiwari et al. 2020; ...
groHMM: a computational tool for identifying unannotated and cell type-specific transcription units from global run-on sequencing data. BMC bioinformatics. 2015;16:222.M. Chae, C. Danko, and W. Kraus, "grohmm: a computational tool for identifying unannotated and cell type-specific transcription ...
groHMM: a computational tool for identifying unannotated and cell type-specific transcription units from global run-on sequencing data. BMC bioinformatics. 2015; 16: 222.M. Chae, C. Danko, and W. Kraus, "grohmm: a computational tool for identifying unannotated and cell type-specific ...
PCR amplification step, which selectively enriches for library fragments that have adapters ligated on both ends, was performed according to the manufacturer's recommenda- tion. Each library was uniquely tagged with one of Illumina's TruSeq LT RNA barcodes to allow library pooling for sequencing....