Glu:Gln比率升高 有许多研究报告称,自闭症患者的血液中谷氨酸与谷氨酰胺(Glu:Gln)的比率升高。 将谷氨酸转化为谷氨酰胺是大脑中处理氨废物的主要方式,这对于避免氨中毒和在突触中谷氨酸的过度积累以减少兴奋性毒性非常关键。因此,血液中Glu:Gln比率的升高可能表明自闭症患者大脑中的氨解毒和谷氨酸循环发自闭症生了变化...
谷氨酸(Glu)是肠内合成谷胱甘肽(GSH)、精氨酸(Arg)和脯氨酸(Pro)的特殊前体,可通过谷氨酰胺酶在小肠内由Gln产生。尽管在任何条件下,Glu是否能有效替代日粮中的Gln尚不清楚,但已经研究证明,向哺乳和断奶仔猪日粮中补充Gln或Glu可改善其全身健康和生长性能,这与肠道的形态和健康改善有关。日粮中添加2%Gln能缓解断...
The substitutions of Gln165 with Glu or Leu have minimal effect on the affinity of the mutants towards GSH or EPNP. However, a discernible reduction in kcatapp was observed. Asp161 is involved in maintaining the structural integrity of the enzyme. The KmGSHapp of the D161L mutant is 616-...
作者发现AGC在四种细胞系中均有表达,UCP2沉默并不影响其表达水平,表明Asp通过AGC的输出依赖于Glu的进入。 进一步研究发现,补充还原性谷胱甘肽(GSH)或N -乙酰半胱氨酸(NAC)能够完全恢复UCP2缺失诱发的生长缺陷,表明UCP2沉默导致KRASmut胞质中Asp的缺失,减少了GSH的可用性并改变了细胞氧化还原稳态。在KRASmut细胞中,UC...
Gln、Glu、Gly和Cys有助于在损伤后重建肠道结构,并在疾病条件下逆转其功能障碍。此外,Met、Lys、Thr和Glu在影响肠腔中不同细菌的生长中起着重要作用。当前,商品饲料中已全面禁止使用抗生素作为生长促进剂,进一步探索单个AA和AA之间的互作对仔猪肠道健康的影响具有十分重要的意义。
On the contrary, the R107E mutant has a K(m)(app)(GSH) and a k(cat)(app) that are 11-fold and 35 % lower than those of the wild-type cGSTM1-1. The substitutions of Gln165 with Glu or Leu have minimal effect on the affinity of the mutants towards GSH or EPNP. However, a ...
单字母: H2N-GIVGTSISLYQLENYNFVNQHLGSHLVEALYLVGEGFFYTPT-OH 三字母: H2N- Gly- Ile- Val- Gly- Thr- Ser- Ile- Ser- Leu- Tyr- Gln- Leu- Glu- Asn- Tyr- Asn- Phe- Val- Asn- Gln- His- Leu- Gly- Ser- His- Leu- Val- Glu- Ala- Leu- Tyr- Leu- Val- Gly- Glu- Gly- Phe-...
2) glutamine [英]['glu:təmi:n] [美]['glutəmin] 谷氨酰胺 1. Removal of glutamic acid from glutamine fermentation broth by electrodialysis; 用电渗析法从谷氨酰胺模拟发酵液中脱除谷氨酸 2. Ab initio Calculation Studies on Thermolysis Mechanism of Glutamine; 谷氨酰胺热分解机理的从头算...
2) Gln 谷氨酰胺 1. GLNs Effect on the Content of MDA, GSH and SOD in Skeletal Muscle of the Exhausting Sports Mice; 谷氨酰胺对力竭性运动大鼠腓肠肌抗氧化能力效果研究 2. GLNs Effect on Concent of MDA. GSH in Myocardium of the Exhausting Swimming Mice; ...
2) Gln 谷氨酰胺 1. GLNs Effect on the Content of MDA, GSH and SOD in Skeletal Muscle of the Exhausting Sports Mice; 谷氨酰胺对力竭性运动大鼠腓肠肌抗氧化能力效果研究 2. GLNs Effect on Concent of MDA. GSH in Myocardium of the Exhausting Swimming Mice; ...