the patient’sblood glucosemust also be monitored periodically to determine the minimumeffective dosefor the patient; to detect primary failure, i.e., inadequate lowering of blood glucose at the maximum recommended
Dose adjustment can be made based on the patient's glycemic control. Maximum recommended dose is 20 mg once daily (2.1). ▪ Administer with breakfast or the first meal of the day (2.1). ▪ For combination therapy with other blood-glucose-lowering agents, initiate the agent at the ...
Dosage adjustments should ordinarily be in increments of 2.5 to 5 mg, as determined by blood glucose response. At least several days should elapse between titration steps. If response to a single dose is not satisfactory, dividing that dose may prove effective. The maximum recommended once daily ...
Dosage adjustment can be made based on the patient’s glycemic control. The maximum recommended dose is 20 mg once daily. Patients receiving immediate release glipizide may be switched to glipizide extended-release tablets once daily at the nearest equivalent total daily dose. 2.2 Use with Other G...
In a peri- and postnatal study in pregnant rats, there was a reduced number of pups born alive following administration of glipizide from gestation day 15 throughout lactation through weaning at doses ≥5 mg/kg/day (about 2 times the recommended maximum human dose based on body surface area...