Take this medication by mouth 30 minutes before breakfast or the first meal of the day as directed by your doctor, usually once daily. Some patients, especially those taking higher doses, may be directed to take this drug twice a day. The dosage is based on your medical condition and resp...
For more severe hyperglycemia (i.e., fasting plasma glucose concentrations of 280–320 mg/dL), consider 2.5 mg of glipizide and 500 mg of metformin hydrochloride as fixed combination twice daily. Efficacy of fixed combination in patients with fasting plasma glucose concentrations >320 mg/dL not ...
When adding GLIPIZIDE XL to other anti-diabetic drugs, initiate GLIPIZIDE XL at 5 mg once daily. Start patients at increased risk for hypoglycemia at a lower dose. When colesevelam is coadministered with glipizide ER, maximum plasma concentration and total exposure to glipizide is reduced. Therefor...
When adding GLUCOTROL XL to other anti-diabetic drugs, initiate GLUCOTROL XL at 5 mg once daily. Start patients at increased risk for hypoglycemia at a lower dose. When colesevelam is coadministered with glipizide ER, maximum plasma concentration and total exposure to glipizide is reduced. Theref...