Renal ImpairmentUse conservative initial and maintenance dosage.Use generally not recommended in patients with severe renal impairment.Cautious dosing recommended.Geriatric PatientsConventional tablets: Initially, 2.5 mg daily.Initially, 5 mg (extended-release tablets) may be used....
Some patients may be effectively controlled on a once-a-day regimen, while others show better response with divided dosing. Total daily doses above 15 mg should ordinarily be divided. Total daily doses above 30 mg have been safely given on ab.i.d.basis to long-term patients. In elderly ...
but greater sensitivity of some individuals cannot be ruled out. Elderly patients are particularly susceptible to the hypoglycemic action of anti-diabetic agents. Hypoglycemia may be difficult to recognize in these patients. Therefore, dosing should be conservative to avoid hypoglycemia[seeDosage and Admi...
but greater sensitivity of some individuals cannot be ruled out. Elderly patients are particularly susceptible to the hypoglycemic action of anti-diabetic agents. Hypoglycemia may be difficult to recognize in these patients. Therefore, dosing should be conservative to avoid hypoglycemia [seeDOSAGE AND AD...