Glioma is the most common primary intracranial tumor in adults, with high incidence, recurrence, and mortality rates [1]. Overall, the broad category of gliomas (ICD-O-3 histology codes 9380–9384 and 9391–9460) represents approximately 24.5% of all primary brain tumors and 80.9% of all mal...
Since NCCN guidelines for risk stratification are considered controversial, we aimed to assess the frequency of initial observation in IDH-mutant gliomas using real-world evidence in the US. METHODS. We evaluated Optum claims from 2016-2021 of patients age 鈮 12 with ICD-10 codes for incident ...
Gliomas are highly infiltrated by bone marrow-derived macrophages and brain-resident microglia, which promote tumor growth and suppress the immune response5. CD40 is expressed on several antigen presenting cells (APCs) and agonistic CD40 antibodies (αCD40) have broad immunostimulatory effects. Indeed, ...
Glioma is the most common primary intracranial tumor in adults, with high incidence, recurrence, and mortality rates [1]. Overall, the broad category of gliomas (ICD-O-3 histology codes 9380–9384 and 9391–9460) represents approximately 24.5% of all primary brain tumors and 80.9% of all mal...