Secondary glioblastoma.This type usually develops from a low-grade glioma – a type of tumor found in the brain or spinal cord. It’s more likely to affect younger people, and it’s usually in the frontal lobe of the brain. The survival rate for this type tends to be better than for ...
The aim of this study was to explore survival and the treatment provided to elderly patients diagnosed with glioblastoma in a population-based setting. We further studied whether increased treatment aggressiveness may have contributed to a clinically important survival benefit in the elderly population. ...
TMZ treatment has been associated with hypermutation status at recurrence28, although hypermutation status has not been reported to convey increased survival4. By contrast, we found that T-cell abundance was correlated with a significant increase in survival (Fig. 5h). This seems to be driven by...
Butterfly glioblastoma (bGBM) is a rare brain tumor that invades both hemispheres by crossing the corpus callosum. bGBM is associated with a dismal prognosis with a median survival time of a few months. Surgical resection is a rare treatment option due t
Glioblastoma survival in the United States improved after Food and Drug Administration approval of bevacizumab: a population-based analysis. Cancer. 2013Johnson, D.R.; Leeper, H.E.; Uhm, J.H. Glioblastoma survival in the United States improved after Food and Drug Administration appro...
The most likely explanation for this change is the approval and use of bevacizumab for progressive glioblastoma, indicating that at a population level, treatment strategies involving bevacizumab prolong survival. Cancer 2013;119:3489–3495.. 2013 American Cancer Society. 展开 关键词: glioblastoma ...
Demographic characteristics, treatment patterns, and overall survival (os) in the elderly and non-elderly groups were compared. Predictors of os were determined using multivariate analysis.Results Elderly patients were more likely to present with a poor performance status (Eastern Cooperative Oncology ...
Patients with a newly diagnosed glioblastoma multiforme (GBM) have a high risk of recurrent disease with a dismal outcome despite intensive treatment of se... E Myra,V Linde,JC Joost,... - 《Oncologist》 被引量: 11发表: 2015年 Surgery, a prognostic marker for progression-free survival? 0...
Survival analysis of HDR brachytherapy versus reoperation versus temozolomide alone: a retrospective cohort analysis of recurrent glioblastoma multiforme Tumour recurrence of glioblastoma multiforme (GBM) after initial treatment with surgical resection, radiotherapy and chemotherapy is an inevitable phenomen... ...
et al. Longterm survival in primary glioblastoma with versus without isocitrate dehydrogenase mutations. Clin. Cancer Res. 19, 5146–5157 (2013). Article CAS PubMed Google Scholar Ward, P. S. et al. The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme ...