Animal experiments were approved by the Medical Ethics Committee of Yan’an People’s Hospital following the UK Animals (Scientific Procedures) Act, 1986 and Animal Research Reporting In Vivo Experiments (ARRIVE) guidelines. Six-week-old female BALB/c nude mice were purchased from GemPharmatech compa...
Breakthrough drug improves treatment of medulloblastoma in mice•Feb. 5, 2025, 12:33 AM ET (News-Medical) brain cancer, the uncontrolled growth of cells in thebrain. The termbrain cancerrefers to any of a variety of tumours affecting different brain cell types. Depending on the location and...
If you have glioblastoma symptoms, your doctor will likely refer you to aneurologist(a doctor who specializes in diagnosing and treating brain disorders).Your neurologist will take your medical history and ask questions, like when your symptoms began, if anything makes them better, and more. The ...
found to be prognostic of improved survival that is independent of age, performance status, the extent of resection, and MGMT methylation status (HR 0.78;p = 0.031). Other limitations have also deterred the widespread adoption of TTF despite its endorsement by the NCCN guidelines [84]. An...
The study was conducted in compliance with the Protocol at 15 clinical trial sites in the United States and Canada, as well as recognized international standards including the Good Clinical Practice guidelines of the International Conference on Harmonisation and the principles of the Declaration of Hels...
Glioblastoma stem cells (GSCs) play a key role in glioblastoma (GBM) resistance to temozolomide (TMZ) chemotherapy. With the increase in research on the tumour microenvironment, exosomes secreted by GSCs have become a new focus in GBM research. However,
Home About Articles Submission Guidelines Submit manuscript Research Open access Published: 29 July 2024 HMGB1/TREM2 positive feedback loop drives the development of radioresistance and immune escape of glioblastoma by regulating TLR4/Akt signaling Hui Qiu, Zhiying Shao, Xin Wen, Debao Qu, ...
Based on the RTOG guidelines, the initial volumes (T2/FLAIR + gross/residual tumor plus resection cavity) receive 4600 cGy/23 fractions followed by a boost to 1400 cGy/7 fractions to gross/residual tumor plus resection cavity. In a study by Kelly et al,15 the isolated tumor cells were ...
(2 h, 4 °C) to pellet small EVs (fixed angle rotor F-37L-8 8x100ml, THERMO WX 100). Isolated small EV populations were characterised according to the latest guidelines of the International Society for Extracellular Vesicles on the Minimal Information Required for Studies of Extracellular...
MRI scans performed on brain tumour bearing mice using a nanoScan PET/MRI scanner (Mediso Medical Imaging Systems, Hungary). Mice were maintained under inhaled isoflurane anaesthesia (induction 5% v/v; maintenance 1.5–2.0% v/v) in the medical air during imaging procedure duration. Whole brain ...