(redirected fromglioblastomas) Thesaurus Medical Related to glioblastomas:meningiomas,gliomas gli·o·blas·to·ma (glē′ō-blă-stō′mə, glī′-) n.pl.gli·o·blas·to·masorgli·o·blas·to·ma·ta(-mə-tə) A malignant tumor of the central nervous system, usually occurring ...
GBMis the most common primarybrain cancer in adults. Despite recent advances in surgical procedures and combinedchemoradiotherapy, the prognosis of GBM remains very poor, with amedian survival timeof less than 1 year[71]. Noninvasive as well as highly sensitive and specific biomarkers for early di...
Glioblastoma (GBM) is the most common malignant primary brain tumor. Despite comprehensive treatment with traditional surgery, radiotherapy, and chemotherapy, the median survival rate is <14.6% and the 5-year survival rate is only 5%. FBXO22, a substrate receptor of the SCF ubiquitin ligases, ha...
Median Survival Time (Months) of Patients with Glioblastoma in Ohio and Taiwan.LiNien ChienQuinn T. OstromHaley GittlemanJiaWei LinAndrew E. SloanGene H. BarnettJ. Bradley ElderChristopher McPhersonRonald WarnickYungHsiao Chiang
(ttfields) have improved the median survival time of glioblastoma, but the time still remains less than 20 months6. Moreover, the median OS time of rGB is only 6–11 months owing to the lack of effective treatments7,8,9. GB is a highly vascularized tumor and expresses a large amount ...
Median survival(MS) was 17 months; median time-to-progression(TTP) 6.8 months. The local and distant groups had comparable prognostic factors. There was no difference in MS(p=0.35) or TTP(p=0.95) by location of recurrence. At relapse, 26 patients(38.8%) received continuous, dose-intense ...
Glioblastoma multiforme (GBM) is a lethal brain tumor with a mean survival time of 1 year. One major reason for therapeutic failure is that GBM cells have an extraordinary capacity to invade normal brain tissue beyond the surgical margin, accounting for the lack of treatment efficacy. GBM cells...
Glioblastoma is the most common, and lethal brain cancer in adults, with a median survival time of less than 15 months, the authors wrote. Tumor relapse, which occurs in more than 90% of patients, represents what the team describe as a major roadblock that contributes to such a “disma...
(see details in the next section). It is interesting to note that three of the 19 fragile miRNAs were significantly related to GBM survival time (univariant cox regression [38]). The three fragil miRNAs include hsa-mir-487b with P-value: 0.0063 and hazard ratio: 1.349; hsa-mir-17-5p ...
Background: Glioblastoma (WHO Grade IV glioma) patients have a dismal prognosis, with a median life expectancy of under two years. The influence of patient socioeconomic status on survival has not been clearly established. Methods: We retrospectively reviewed glioblastoma patients seen and treated at...