Exploring the potential impact of probiotic use on drug metabolism and efficacy Biomedicine & Pharmacotherapy Journal2023, Biomedicine & Pharmacotherapy Carmen Purdel, ... Denisa Margină 6.3 Antidiabetic drug
It should be kept out of reach of children and should not be used after the expiration date. Inappropriate storage conditions, such as exposure to excessive heat or humidity, may affect the stability and efficacy of the drug. It is essential to follow storage guidelines to ensure that ...
Administration of gliclazide to type 2 diabetic patients could form part of the strategy for the prevention and management of diabetic cardiovascular diseases Drug interactions Potentially hazardous interactions with other drugs Analgesics: effects enhanced by NSAIDs. Antibacterials: effects enhanced by ...
Ambrogi V, Perioli L, Ciarnelli V, Nocchetti M, Rossi C (2009) Effect of gliclazide immobilization into layered double hydroxide on drug release. Eur J Pharm Biopharm 73:285-291Ambrogi V, Perioli L, Ciarnelli V,etal. Effect of gliclazide immobilization into layered double hydroxide on ...
Combination drug research[1-3] Report 1, Meng Yufen, Department of Endocrinology, Minquan County People's Hospital, studied the therapeutic effect of acarbose combined with Gliclazide sustained-release tablets on type 2 diabetes (T2DM) in the elderly. Methods: 82 elderly T2DM patients admitted to...
Gliclazide is a second generation anti-diabetic drug used for the treatment of type II diabetes. The drawback of the drug is, it is practically insoluble in water and so possesses poor solubility, GI absorption and bioavailability. Hence the objective of the work is to develop mouth dissolving...
Drug delivery and therapeutic challenges of gliclazide, a BCS class II drug used in type 2 diabetes mellitus (T2DM) can be overcome by exploring smarter carriers of second-generation nanocrystals (SGNCs). A combined method of emulsion diffusion, high-pressure homogenization and solvent evaporation me...
data from RWE inform regulatory authorities on long-term drug safety, and increasingly it also informs the clinical decision-making process over the life cycle of the drug. Lastly, RWE can provide insights on patients’ perspectives that are not routinely captured in RCTs and might be subject to...
An advanced microencapsulated system: a platform for optimized oral delivery of antidiabetic drug-bile acid formulations Introduction: In previous studies, we have shown that a gliclazide-cholic acid derivative (G-CA) mixture resulted in an enhanced ileal permeation of G (ex ... Armin Mooranian,...
An event is serious (FDA MedWatch definition) when the patient outcome is: death life-threatening hospitalisation disability congenital anomaly requires intervention to prevent permanent impairment or damage Drug overdose A 46-year-old man developed hypoglycaemia following a gliclazide overdose. He was ...