2022,The Neurobiology, Physiology, and Psychology of Pain Chapter Peripheral glia physiology and function 3.3.2Satellite glia of sensory and autonomic ganglia Satellite glia are the main glial cell type in sensory ganglia, but they also contain myelinating and nonmyelinatingSchwann cells. Eachsensory...
A.Verkhratsky,V.Parpura, inReference Module in Neuroscience and Biobehavioral Psychology, 2017 Conclusion Glial cellsare at least as abundant as neurons and it has become evident now that one can only understand brain function by studying the interaction between glial cells and neurons. The last...
However, while many studies support TSPO as a glial marker in humans, it is important to note that not all studies have detected TSPO upregulation in diseases with a presumed inflammatory component: for example, prior research showed no differences in TSPO PET signal in cocaineaddictionand...
TLR4, for example, has been observed on microglia, neurons, astrocytes, neural progenitor cells, and endothelial cells (Alfonso- Loeches et al, 2010; Grace et al, 2014b; Jack et al, 2005; June et al, 2015; Liu et al, 2011; Rolls et al, 2007). Advanced transcriptome analysis of ...
In the central nervous system, bidirectional signaling between glial cells and neurons (‘neuroimmune communication’) facilitates the development of persistent pain. Spinal glia can contribute to heightened pain states by a prolonged release of neurokin
there are canonical regulators. For example, abolishing Wnt signalling in OPCs has been shown to reduce monocyte accumulation and astrocyte hypertrophy95. Furthermore, neurons themselves are directly contacted by cells in a manner which inhibits reestablishment of neuronal connectivity. Proinflammatory ED1...
implications for disease etiology and the female predominance of persistent pain KN Dodds1, EAH Beckett1, SF Evans2,3, PM Grace2,4, LR Watkins4 and MR Hutchinson1,5 In the central nervous system, bidirectional signaling between glial cells and neurons ('neuroimmune communication') facilitates th...
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