Mol. Formula C30H35N7O4S Mol. Weight 589.71 Qty 1 2.5mg Qty 2 25mg Appearance Off-White Solid Application Notes A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). Syno...
Imatinib mesylate is a white to off-white to brownish or yellowish tinged crystalline powder. Its molecular formula is C29H31N7O • CH4SO3and its molecular weight is 589.7. Imatinib mesylate is soluble in aqueous buffers less than or equal to pH 5.5 but is very slightly soluble to insolub...
GLEEVEC PROCESSThe invention provides a process for the production of a pharmaceutical intermediate compound in accordance with the following scheme (formula (I)), wherein R5 is any suitable substituent group; and Z is any suitable leaving group.doi:WO2006061332 A1Mccormack, Peter...
Gleevec-d8 (Imatinib-d8) structure CAS No. Chemical Name: Gleevec-d8 (Imatinib-d8) Synonyms Gleevec-d8 (Imatinib-d8) CBNumber: CB92509384 Molecular Formula: C30H27D8N7O4S Molecular Weight: 0 MDL Number: MOL File: Mol file Request For QuotationProperties Uses Suppliers 1 ...
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Subsequently, the quantity of KAI1 compared to GAPDH gene expressions were analyzed using the formula; 2-DDCt.Results: Imatinib was showed to have a dose-dependent inhibitory effect on the viability of MCF-7 cells. CD82/GAPDH gene expression ratios were 1.322 卤 0.030(P > 0.05)...
Subsequently, the quantity of KAI1 compared to GAPDH gene expressions were analyzed using the formula; 2-DDCt.Results: Imatinib was showed to have a dose-dependent inhibitory effect on the viability of MCF-7 cells. CD82/GAPDH gene expression ratios were 1.322 卤 0.030(P > 0.05),2.052 卤 ...