参考文献 1. Gleason DF, Mellinger GT. Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging. The Journal of urology. 1974;111:58-64. 2. Jackson W, Hamstra DA, Johnson S, et al. Gleason pattern 5 ...
Clinical and molecular rationale to retain the cancer descriptor for Gleason score 6 diseaseDiagnosis• Diagnostic markers• Prognosis• Prostate cancerTreatment choices for men with indolent prostate cancer include active surveillance or definitive local therapy. Overtreatment of these patients is an ...
INTRODUCTION In cases of low-grade prostate cancer with a Gleason score (GS) of 6, extraprostatic extension and metastasis have been shown to be less likely to occur, and such cases gen- erally accompany a good prognosis. Accordingly, such cas- es have been known...
Gleason Score 7. Patients whose tumors have aGleason scoreof 7 have a significantly worse prognosis than those with a Gleason score of 6. Given the adverse prognosis associated with Gleason pattern 4, one would expect that whether a tumor is Gleason score 3 + 4 or 4 + 3 would influence ...
Score: 4.7/5(45 votes) The Gleason grading system is used to help evaluate the prognosis of men with prostate cancer using samples from a prostate biopsy. Together with other parameters, it is incorporated into a strategy of prostate cancer staging which predicts prognosis and helps guide therapy...
GleasonScore、ECT Abstract Backgroundprostatecancerisacommoncancerofmen,andtheisrasingin China.thetreatmentofprostatecancerisrelayedontheGleasonscoreof theneedlebiopsy.However,theGleasonscoreoftheneedlebiopsytissueis notaccurate.TheserumPSAiswidelyusedinthediagnosis,duringthe treatmentandpredictingtheprognosisnowdays....
[Key words]Prostatic neoplasm; Prostate-specific antigen; Gleason score; Cancer outcome 前列腺特异性抗原(prostate-specific antigen,PSA)作为前列腺癌筛查指标已在全世界范围内广泛应用,其水平高低在筛选合适穿刺患者、已确诊患者治疗方式抉择...
9、nthemajorityoftheworld.Gleasongradingisoneofthemostimportantpredictorsofprognosisforpatientswithcancerandtodatemorethan40gradingsystemshavebeenproposedforprostatecarcinoma.However,fewresearchesfocusonclinicalfeaturesindifferentsubgroupofGleasonscore8patients.Therefore,tobetterunderitsassociationandi 10、nvestigatethesurvi...
level(HR=1.352),high Gleason score(HR=4.576),TNM staging(HR=2.937)and bone metastasis(HR= 1.258)were independent risk factors for prognosis in PCa patients(P<0.05).The former high TT level(HR= 0.063)was a protective factor for the prognosis of PCa patients(P<0.05).The ROC ...
按照以上方法记录每例穿刺标本主要结构成分和次要结构成分之和,得出 Gleason 评分(Gleason score,GS)。 2 结果 31例穿刺标本Gleeson评分按照6分、7分和8～10分为3组,其中6分占16.1%(5/31),7分占61.3%(19/31),8 ～10 分占 22.6%(7/31)。以 3级为主要结构成分占48.4%(15/31),次要结构成分占51.6%(...