Sequence variants and/or copy number variants (deletions/duplications) within the GLCCI1 gene will be detected with >99% sensitivity. Variants classified as unknown significance (VUS), likely pathogenic, or pathogenic will be reported. Benign and lik...
GLCCI1 (glucocorticoid induced transcript 1), also known as TSSN1, GIG18 or FAM117C, is a 547 amino acid protein found in thymus and CD4+CD8+ cells during specific stages of spermatogenesis in testis. Subject to phosphoryla- tion, GLCCI1 is encoded by a gene located on human chromosome...
英文摘要: OBJECTIVE:To study the value of ADRB2,GLCCI1,FCER2 gene detection in individualized medication of children with refractory asthma. METHODS:Clinical pharmacists participated in therapy for 2 cases of refractory asthma,and comprehensively analyzed risk factors as its pathogenic factors (allergens...
Gene ID (NCBI) 113263 Alternative Names GLCCI1; FAM117C; GCTR; GIG18; TSSN1; glucocorticoid induced 1 Application Notes: The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. ...
KEY WORDS: Bronchial asthma; Gene polymorphism; Pulmonary function index; Airway hyperresponsiveness 0 引言 支气管哮喘（Asthma）是由多种炎症细胞参与的一种慢性呼吸系统疾病，其炎症特征主要由于炎性细胞浸润气道，致使气流阻塞从而引起喘息、咳嗽、胸闷、呼吸困难为发病特 征的慢性疾病[1，2]。哮喘虽然是一种...
Here, the distribution of functionally relevant single nucleotide polymorphisms (SNP) belonging to the GC-induced transcript 1 GLCCI1 (rs37972) and the glucocorticoid receptor (rs41423247, rs6195 and rs6198) gene loci were analyzed alongside clinical factors for their association with the response ...
免疫原序列 MPLSNISVPKSSVSRVPCNVEGISPELEKVFIKENNGKEEVSKPLDIPDGRRAPLPAHYRSSSTRSIDTQTPSVQERSSSCSSHSPCVSPFCPPESQDGSPCSTEDLLYDRDKDSGSSSPLPKYASSPKPNNSYMFKRE UniProt登记号 Q86VQ1 运输 wet ice 储存温度 −20℃ Gene Information human ... GLCCI1(113263) 安全信息 ...
Recently a novel pharmacogenetic variation in the glucocorticoid-induced transcript 1 gene (GLCCI1) has been studied intensively in asthma7–11, since Tantisira and colleagues revealed in 2011 that the functional rs37973 polymorphism, which was in complete linkage disequilibrium with rs37972, might ...
GLCCI1[HGNC][GeneCards][NCBI] 基因种类(locus group) protein-coding gene 同源简称(alias symbol) GIG18|FAM117C|TSSN1 基因家族代码(gene_family_id) [HGNC][GenScript] omim代码 614283 entrez码 113263[Vega] ensembl基因码 ENSG00000106415[Ensembl] ...
Single nucleotide polymorphisms (SNPs) have been recently identified in the promoter region of glucocorticoid-induced transcript 1 gene (GLCCI1) which affect steroid-responsiveness in asthmatic patients. Independently, GLCCI1 was identified as a podocyte protein, the loss of which disrupts the function...