Transferring from Other Insulins to Insulin Glargine Sub-Q Transferring from one 100-unit/mL preparation of insulin glargine to another (i.e., Lantus to Basaglar). Dosage of Basaglar should be the same as that of the other preparation; administration time determined by clinician....
Fasting insulin secretion↑↑↑ Postprandial insulin secretion↓↑ Glucagon secretion↓↓ Gastric emptying rate↓↔ Blood pressure↓↓ Heart rate↔/↑↑ Body weight reduction↓↓↓ View article Emerging Therapeutics for Diabetes, Obesity, and Related Complications ...
In mice and rats, standard two-year carcinogenicity studies with insulin glargine were performed at doses up to 0.455 mg/kg, which was for the rat approximately 65 times the recommended human subcutaneous starting dose of 0.2 Units/kg/day (0.007 mg/kg/day). The findings in female mice were...
Another aspect of the present invention is the use of a combination of (a) desPro36Exendin-4(1-39)-Lys6-NH2 or/and a pharmaceutically acceptable salt thereof, and (b) insulin glargine or/and a pharmaceutically acceptable salt thereof, wherein the concentration of compound (a) is in ...