Giant CellDenosumabMultinucleated Giant CellGiant Cell TumorGiant Cell TumorSkeletal Radiology -Zhang, YaxiaCleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, USAIlaslan, HakanDepartment of Diagnostic Radiology, Cleveland Clinic, Cleveland, USABauer, Thomas W....
摘要: A malignant giant cell tumor of the carpal bones metastatic to the lung in a 23-year-old woman is described. Findings from ultrastructural and cell marker studies support the concept that this tumor is of histiocytic origin.关键词:...
Giant cell tumour of bone (GCTB) is a rare osteolytic tumour that is responsible for approximately 6 % of all primary bone tumours. Reported annual incidence ranges between 1 and 6 per 10 million persons [1,2] to approximately 1 per million in the US, Western Australia, Japan and Sweden...
Giant cell tumor of bone (GCTB) was first described by Jaffe et al.1in 1940 and makes up about five percent of all primary bone lesions2,3; GCTB is typically located in the epiphyseal region of the long tubular bones such as the distal femur and the proximal tibia3,4. Based on the...
Giant-cell tumor is a rare benign tumor that generally arises in long bones of the lower extremity in adults. The involvement of the metacarpal bone in children is extremely rare. The authors report the case of an 8-year-old boy admitted for a painless swelling of the posterior surface of...
A young adult patient might present with a classic triad of pain, swelling, and altered gait.3 Paget's disease also presents a risk factor in the development of GCTB in males which has an earlier age of onset and a higher mortality rate.2 The Giant Cell tumor of bone can be divided ...
Giant-cell-rich tumors of bone Jeremiah F.Molligan,Andrew E.Rosenberg, inDiagnostic Histopathology, 2022 Giant cell tumor of bone Giant cell tumor of bone(GCT) is a locally aggressive, and rarely metastasizing neoplasm of bone, and is the most common giant cell rich lesion of theskeleton. It...
Denosumab Induces Tumor Reduction and Bone Formation in Patients with Giant-Cell Tumor of Bone Giant-cell tumor of bone (GCTB) is a locally aggressive, benign osteolytic tumor in which bone destruction is mediated by RANK ligand (RANKL). The RANKL in... D.,G.,Branstetter,... - 《Clinica...
This case reports the synchronous diagnosis of two rare unrelated diseases; leiomyosarcoma and tenosynovial giant cell tumor of the knee. It focuses on the challenges of diagnosing tenosynovial giant cell tumor, including cognitive biases in clinical medicine that delay diagnosis. It also demonstrates ...
Histology of the biopsy demonstrated a low grade fibrohistiocytic tumour and favoured the diagnosis of tenosynovial giant cell tumour. The specimen was of fibrotendinous connective tissue, with proliferation of mononuclear epithelioid to spindled cells within the fibrotic stroma. There was mild nuclear...