传统的 GFR 评估方法依赖于血清肌酐的单次测量,并结合经验公式估算,但这种方法存在准确性问题。 7月 2 日,一项发表在《Kidney International》的前瞻性、开放标签、 II 期临床试验研究,验证了新型荧光示踪剂 Relmapirazin(MB-102)作为 GFR 示踪剂的临床有效性。 图源:参考文献[1] 该项研究在 3 个临床中心开展,...
2 Stevens LA, Levey AS. Measured GFR as a confirmatory test for estimated GFR. J Am Soc Nephrol 2009;20:2305–13. 3 Stevens LA, Coresh J, Greene T, et al. Assessing kidney function—measured and estimated glomerular filtration rate. N Engl J Med 2006;354:2473–83. 4 Schwartz GJ, Mu...
2 Stevens LA, Levey AS. Measured GFR as a confirmatory test for estimated GFR. J Am Soc Nephrol 2009;20:2305–13. 3 Stevens LA, Coresh J, Greene T, et al. Assessing kidney function—measured and estimated glomerular filtration rate. N Engl J Me...
5. Schaeffner E S , Ebert N , Delanaye P , et al. Two Novel Equations to Estimate Kidney Function in Persons Aged 70 Years or Older[J]. Annals of Internal Medicine, 2012, 157(7):471-81. 6. 王寅, 王蓓莉综述, 郭玮, 等. 肾小球...
function. Whereas we might deduce that a stable GFR implies stable disease, this is not always the case. There is not a directly proportional relationship between the loss of kidney function and loss of kidney mass. The kidney can compensate for loss in renal function by increasing it’s ...
5. Schaeffner E S , Ebert N , Delanaye P , et al. Two Novel Equations to Estimate Kidney Function in Persons Aged 70 Years or Older[J]. Annals of Internal Medicine, 2012, 157(7):471-81. 6. 王寅, 王蓓莉综述, 郭玮, 等. 肾小球滤过率计算公式的发展和比较 [J]. 检验医学, 2015,...
5. Schaeffner E S , Ebert N , Delanaye P , et al. Two Novel Equations to Estimate Kidney Function in Persons Aged 70 Years or Older[J]. Annals of Internal Medicine, 2012, 157(7):471-81. 6. 王寅, 王蓓莉综述, 郭玮, 等. 肾小球滤过率计算公式的发展和比较 [J]. 检验医学, 2015,...
5. Schaeffner E S , Ebert N , Delanaye P , et al. Two Novel Equations to Estimate Kidney Function in Persons Aged 70 Years or Older[J]. Annals of Internal Medicine, 2012, 157(7):471-81. 6. 王寅, 王蓓莉综述, 郭玮, 等. 肾小球滤过率计算公式的发展和比较 [J]. 检验医学, 2015,...
swelling or puffiness around your eyes, belly, wrists, or ankles, or pain in the middle of your back, near your kidneys. If your doctor notices a change in your kidney function from a blood and/or urine test, they can come up with a treatment plan for you that may include medications...
(e.g. inulin, iohexol, iothalamate, etc.) to determine pharmacokinetic or pharmacodynamic alterations due to kidney dysfunction. FDA KDIGO. Released draft. Guidance for Industry: Pharmacokinetics in Patients with Impaired Renal Function - Study Design, Data Analysis, and Impact on Dosing and ...