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Chronic kidney disease can progress to the end-stage renal disease (ESRD) characterized by a high risk of morbidity and mortality. ESRD requires immediate therapy or even dialysis or kidney transplantation, therefore, its timely diagnostics is critical for many patients. ESRD is associated with patho...
(particularly in relation to age-related decline),21 the fact that most estimated GFR equations do not seem to be able to identify most hyperfiltrating patients,94 and that renal function is often standardised for body mass.22 Early biomarkers are thus lacking to identify and stage clinically ...
Since 1957, over 70 equations based on creatinine and/or cystatin C levels have been developed to estimate glomerular filtration rate (GFR). However, whether these equations accurately reflect renal function is debated. In this Perspectives article, we d
ESRD[EndStage Renal Disease】 终末期肾病 SCr【SerumCreatinine】 血清肌酐 GFR[Glomemlar Filtration Rate,ml/min/1.73m2] 肾小球滤过率 CysC【CystatinC】 血清胱抑素C CCr【CreatinineClearance】 内生肌酐清除率 CRF【Chomc Renal Failure] 慢性肾功能衰竭 ...
The economic impact of this is significant considering the value associated with the part when it reaches the assembly stage. The quality of the drilled holes such as waviness/roughness of its wall surface, axial straightness and roundness of the hole cross-section can cause high stresses on the...
1585Background: Chronic renal failure (CRF) leads to end stage renal disease (ESRD). As the incidence of ESRD is rapidly increasing, the demand for dialysis and renal transplantation has dramatically increased. Human leukocyte antigens (HLA) have been found to be associated with the pathogenesis...
Two studies published recently in Nature Genetics have reported that genetic variation at the MYH9 locus of chromosome 22 can explain much of the increased risks of end-stage renal disease and focal segmental glomerulosclerosis (FSGS) among African Americans. Kopp et al. performed genome-wide ...
Chen DC, Shlipak MG, Scherzer R, et al. Association of intraindividual difference in estimated glomerular filtration rate by creatinine vs cystatin C and end-stage kidney disease and mortality.JAMA Netw Open. 2022;5(2):e2148940. doi: 10.1001/jamanetworkopen.2021.48940. ...
Two studies published recently in Nature Genetics have reported that genetic variation at the MYH9 locus of chromosome 22 can explain much of the increased risks of end-stage renal disease and focal segmental glomerulosclerosis (FSGS) among African Americans. Kopp et al. performed genome-wide ...