Elacridar (GF120918)是一种有效的P-gp (MDR-1) 和 BCRP 抑制剂。 分子式:C34H33N3O5分子量:563.64 溶解性:溶于DMSO(>30mg/ml) 储存条件:-20°C密闭防潮 运输条件:2~8℃运输 生物活性 产品描述Elacridar (GF120918)是一种有效的P-gp(MDR-1) 和 BCRP 抑制剂。
GF120918 (Elacridar) is a very potent inhibitor of the ABC transporters (P-glycoprotein, P-gp) and BCRP. It reverses multidrug resistance at 0.02 to 0.1 µM in vitro. By blocking the activity of ABC transporter, GF120918 effectively increases the cellular concentration and subsequently ...
Elacridar (GF120918, GW0918, GG918, GW120918),又称依克立达,是可口服的P-glycoprotein (P-gp)选择性抑制剂,IC 50 值为193 nM,也是乳腺癌抗性蛋白(BCRP)的抑制剂。 产品性质 英文别名(English Synonym) Elacridar, GF120918, GW0918, GG918, GW120918 ...
展会 最近搜索:推荐工具:批量查询CAS转化学名CAS校验 结构式搜索委托采购 Elacridar (GF120918; GW0918; GG918; GW120918) 价格电议 起批量≥1 最小起订电询 供货总量电询 发货地址上海市浦东新区 建议售价￥电议 更新日期2025年03月07日 即时洽谈立即询价查看联系方式 ...
Elacridar (GF120918),Elacridar (GF120918)是一种有效的P-gp (MDR-1) 和 BCRP 抑制剂。 AbMole成立于美国休斯敦,经过10年发展,拥有超过8000个高品质现货抑制剂、激动剂(大包装产品价格极优惠);其高品质的人源化单抗抑制剂、真核表达
GF120918, at 250 ng/ml, increased the sensitivity of a P-glycoprotein (P-gp)-mediated multidrug resistant (MDR) small cell lung cancer cell line (H69/LX4) to the P-gp substrates, paclitaxel, taxotere, vinblastine, vinorelbine, daunorubicin and etoposide to levels which were either greater ...
We found that GF120918 treatment severely inhibited parasite invasion and replication. Further analyses of the molecular mechanisms involved revealed that the P-gp inhibitor modulated parasite motility, microneme secretion and egress from the host cell, all cellular processes known to depend on Ca2+...
【药物名称】Elacridar, GW-120918, GF-120918A(HCl), GW-918, GG-918, GF-120918 化学结构式(Chemical Structure):参考文献No. 18191 标题: Acridine derivs. 作者: Duma顃re, B.A.; Dodic, N. (GlaxoSmithKline plc) 来源: EP 0494623; EP 0569380; JP 1994506440; US 5604237; WO 9212132合成路线...
Elacridar_GF120918更新时间:2025/1/15 7:16:34 价格:￥电议 型号:产地:中国大陆热度:2085次简要描述:Elacridar是一种有效的P-糖蛋白(P-glycoprotein)和BCRP的抑制剂,常用于癌症研究产品详情 Elacridar是一种有效的P-糖蛋白(P-glycoprotein)和BCRP的抑制剂,常用于癌症研究体外Elacridar通过[3H]叠氮平抑制P-糖蛋白...
简介内容:Elacridar (GG918) (GF120918) is an effective BCRP and P-gp (MDR-1) inhibitor. 详细内容/Content Product Introduction Bioactivity 名称:Elacridar;依克立达 描述: 依克立达。 关键字:GW0918|GW120918|GF120918|GG918;GW0918|依克立达|GW120918|GF120918|GG918| ...