Adding published GDM cord blood DNAm data we segregated patients based on treatment (Diet Only vs. +Insulin) and identified altered CpG sites to be unique to each GDM treatment group. Conclusion: Consistency in findings with other studies provides evidence for the role of DNAm in placental and...
Gestational diabetes mellitus (GDM), a common pregnancy disease, has long-term negative effects on offspring health. Epigenetic changes may have important contributions to that, but the underlying mechanisms are not well understood. Here, we report the influence of GDM on DNA methylation of offspring...
Gestational diabetes mellitus epigenetically affects genes predomi- nantly involved in metabolic diseases. Epigenetics 2013;8: 935-43.Ruchat SM, Houde AA, Voisin G, St-Pierre J, Perron P, Baillargeon JP, et al. Gestational diabetes melli- tus epigenetically affects genes predominantly involved in...
Methylation of HIF3A promoter CpG islands contributes to insulin resistance in gestational diabetes mellitusgestational diabetes mellitus (GDM)HIF3AmethylationBackgroundGestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance during pregnancy, and will lead to high risk of ...
Gestational diabetes mellitus (GDM) significantly impacts maternal and infant health both immediately and over the long term, yet effective early diagnostic biomarkers are currently lacking. Thus, it is essential to identify early diagnostic biomarkers f
18. Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) https://guidelines.diabetes.ca/cpg/chapter2. Accessed 15 April 2023. 19. Hedderson, M. M. et al. A tailored letter based on electronic health record data improves gestational weight gain among women with ...
Gestational diabetes mellitus (GDM) affects approximately 10 % of pregnancies in the United States and increases the risk of adverse health outcomes in the offspring. These adult disease propensities may be set by anatomical and molecular alteration
The Center for Disease Control and Prevention ranks diabetes mellitus (DM) as the seventh leading cause of death in the USA. The most prevalent forms of DM include Type 2 DM, Type 1 DM, and gestation...
births showing a higher frequency of female (34.6% males; 65.4% females) and LGA births a higher frequency of male newborns (69.0% males; 31.0% females). Moreover, the distribution of the mothers who suffered from diabetes mellitus during pregnancy was significantly shifted towards LGA newborns ...
Excessive gestational weight gain (GWG) and pre-pregnancy obesity are associated with higher risk of adverse pregnancy outcomes, such as macrosomia, gestational diabetes mellitus (GDM), preeclampsia, and caesarean delivery [1]. Several factors influence GWG, including quality of diet, physical activity...