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4 The genetics of gestational diabetes mellitus: evidence for relationship with type 2 diabetes mellitus Julie Robitaille, PhD1, and Althea M. Grant, PhD2 Gestational diabetes is a major public health problem because of its prevalence, its associated complications during pregnancy, and its increased...
Huvinen E, Eriksson JG, Koivusalo SB, Grotenfelt N, Tiitinen A, Stach- Lempinen B, et al. Heterogeneity of gestational diabetes (GDM) and long- term risk of diabetes and metabolic syndrome: findings from the RADIEL study follow-up. Acta Diabetol. 2018;55:493-501....
specifically through aberrant maternal immunity, differential GBS transcriptional adaptation, and altered composition of the vaginal microbiota during pregnancy. Considering the altered metabolic, immune, and microbial profiles in gestational diabetes compared to non-diabetic pregnancy,...
This systematic review to support the 2021 US Preventive Services Task Force Recommendation Statement on screening for gestational diabetes summarizes
suggesting that lower nephron numbers may result from exposure toin-uterogestational diabetes [96]. Additionally, maternal diabetes is associated with a threefold increase in the risk of renal abnormalities, such as renal agenesis and dysgenesis [97]. These findings highlight the long-term renal imp...
Predictor set 1 were sourced from the existing, internationally validated Monash GDM model: GDM history, body mass index, ethnicity, age, family history of diabetes, and past poor obstetric history. New models with different predictors were developed, considering statistical principles with inclusion ...
International Journal of Women's Health Dovepress open access to scientific and medical research Open Access Full Text Article Original Research Prevention of gestational diabetes with a prepregnancy lifestyle intervention – findings from a randomized controlled trial This article was published in the ...
Bosmans, PhD JAMA Key Points Question Does early metformin initiation improve glycemic control and reduce insulin use in pregnant individuals with gestational diabetes? Findings In this randomized clinical trial, the composite outcome of insulin initiation and a fasting glucose level of 5.1 mmol/L (92...
doi:10.1001/jamanetworkopen.2023.0672 Key Points Question Is exposure to gestational diabetes, gestational hypertension, or preeclampsia associated with biological gestational age, measured via epigenetic clocks, in newborns? Findings In this national multisite cohort study of 1801 children, preeclampsia and...