Mutations in the L1 gene are responsible for four X linked neurological conditions: X linked hydrocephalus (HSAS), MASA syndrome, complicated spastic paraplegia type 1 (SP-1), and X linked agenesis of the corpus callosum. As the clinical picture of these four L1 associated diseases shows ...
No genotype/phenotype correlation for mutations in the TGM1 gene was found in this group of patients, which included two unrelated patients homozygous for the same mutation. Similarly, no clear difference in the clinical picture was seen between patients with TGM1 mutations and those unlinked to ...
The cover picture shows a selection cycle for evolving protein binders in the "test tube" with an in vitro genotype–phenotype linkage based on O6-alkylguanine alkyltransferase (AGT) and in vitro compartmentalisation. The protein of interest was fused to AGT, expressed in vitro by using a ...
aha is running in the gym in picturel ha在体操里在picturel跑 [translate] ai meet a lot of people and have a lot of diferent conversations it is a nice job 我遇见很多人民并且有它是一个好的工作的很多不同的交谈 [translate] aCombined analysis revealed 显露的联合的分析 [translate] asnag ...
This biologic study emphasizes the complex mechanisms for both quantitative and qualitative VWF defects in VWD. In addition, this study provides a new epidemiologic picture of the most bleeding forms of VWD in which qualitative defects are predominant. 展开 ...
Next, we used the established WB-HBs assay to analyze the SHBs isomers in serum samples from 328 patients. All testing samples, in which the lowest level of serum HBsAg was 2.8 log10 IU/ml (676.0 IU/ml), gave measurable signals. Figure 3 was a representative WB-HBs picture showing the...
The overall clinical and histopathological picture is consistent with a delayed-type hypersensitivity (DTH) response to the metal debris shed from the prostheses10. Initially thought to be an idiopathic, rare phenomenon, failure of MoM THRs secondary to ALVAL has been reported to reach over 30% ...
In addition, a novel subgenotype was identified that was basal to the other East Mediterranean sublineages, comprising two Greek strains. The majority of the isolates can be assumed to be of endemic origin, as they were clustered with strains from the Western Balkans or Turkey, whereas one ...
A genome scan using such a multivariate approach will pick up QTL that affect growth in this particular period. However, a disadvantage of this approach is that loci that affect only few traits will be missed and given the pleiotropic nature of most QTL does not yield a picture of when ...
Despite its prominence in plant-microbe interactions, however, no studies have presented a thorough characterization of the Medicago microbiome grown in native soil, so to date we have an incomplete picture of the microbiome of this species beyond its interaction with Ensifer rhizobia. Here we first...