et al. 2014 Genotype and phenotype frequencies of paraoxonase 1 in fertile and infertile men. Syst Biol Reprod Med.60, 361-6.Tavilani, H., Fattahi, A., Esfahani, M., Khodadadi, I., Karimi, K., Bahrayni, E., ... Latifi, Z. (2014). Genotype and phenotype frequencies of para- ...
The genotype/phenotype correlations and gene frequencies have significant impact on genetic counseling of at-risk couples and the future need for therapy of affected patients. 展开 关键词: polynucleotide immunization replicative RNA untranslated regions tumor antigen transgene gene therapy DOI: 10.1089/...
In the context of genetics, especially Mendelian genetics, genotype, and phenotype are two important concepts. The genotype of an organism refers to the actual genetic makeup that the organism has. In contrast, the phenotype of an organism is the actual observable trai...
Eight of these 17 β-thalassemia alleles accounted for 97.4%, others were found at lower frequencies (< 1.0%). Of the 849 cases, 626 were investigated for common α-thalassemia mutations and 155 (24.8%) were found to be co-inherited with different forms of α-thalassemia. Comparison of ...
JinT; ZhangX; GengT; etal.Genotypephenotype analysis of CYP2C 19 in the Tibetan population and its potential clinical implications in drug therapy.Mol ... T Jin,X Zhang,T Geng,... - 《Molecular Medicine Reports》 被引量: 5发表: 2016年 Genotype-phenotype analysis of CYP2C19 in the Tibeta...
However, the function of the APC protein and its role in intestinal tumorigenesis are still elusive. Somatic mutations in the APC gene have also been found in the majority of early sporadic adenomas with similar frequencies as those reported in the more advanced colorectal tumors, clearly ...
2.the sum total of genes transmitted from parent to offspring. Comparephenotype. [< GermanGenotypus(1909); seegene,-o-,-type] gen`o•typ′ic(-ˈtɪp ɪk)gen`o•typ′i•cal,adj. Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005,...
The inter-alpha-trypsin inhibitor (ITI) polymorphism was analyzed in an African Negroid population using polyacrylamide gel isoelectric focusing and subsequent immunoblotting. Gene frequencies of ITI*1, ITI*2, ITI*3 and ITI*4 were calculated to be 0.564, 0.083, 0.337 and 0.004, respectively. One...
How might genotype frequencies change under directional selection? What do autosomal genes determine? What is the difference between a gene and an allele? What is the genotype of a carrier of a recessive disorder? What is the difference between genotype and phenotype? How do these two terms rela...
28 January 2008 / Published online: 26 February 2008 Ó The Japan Society of Human Genetics and Springer 2008 Abstract The aims of our research were to define the genotype–phenotype correlations of mutations in the phenylalanine hydroxylase (PAH) gene that cause phenyl- ketonuria (PKU) among...