Genotype and phenotype frequencies of paraoxonase 1 in fertile and infertile men.Introduction: Paraoxonasel (PON1) is a glycoprotein associated with high density lipoprotein and has antioxidant activity. The impact of PON1 in various stages of spermatogenesis has also been suggested. Materials and ...
Eight of these 17 β-thalassemia alleles accounted for 97.4%, others were found at lower frequencies (< 1.0%). Of the 849 cases, 626 were investigated for common α-thalassemia mutations and 155 (24.8%) were found to be co-inherited with different forms of α-thalassemia. Comparison of ...
However, the function of the APC protein and its role in intestinal tumorigenesis are still elusive. Somatic mutations in the APC gene have also been found in the majority of early sporadic adenomas with similar frequencies as those reported in the more advanced colorectal tumors, clearly ...
Saeed LH; Mayet AY.Genotype-phenotype analysis of CYP2C19 in healthy Saudi individuals and its potential clinical implication in drug therapy.Int J Med Sci... LH Saeed,AY Mayet - 《International Journal of Medical Sciences》 被引量: 19发表: 2013年 Genotype-phenotype analysis of CYP2C19 in the...
The inter-alpha-trypsin inhibitor (ITI) polymorphism was analyzed in an African Negroid population using polyacrylamide gel isoelectric focusing and subsequent immunoblotting. Gene frequencies of ITI*1, ITI*2, ITI*3 and ITI*4 were calculated to be 0.564, 0.083, 0.337 and 0.004, respectively. One...
Heterozygous individuals displayed an intermediate phenotype [17]. However, limited information is available for Jordanian and Sudanese populations regarding the distribution of C3435T polymorphism. The present study investigated the frequencies of the MDR-1 (C3435T) gene polymorphism in 116 Jordanians ...
investigate the dynamics of polymorphisms in an environmental context, that is how phenotype and genotype frequencies change over time and space, and which ... T Backeljau,A Baur,B Baur 被引量: 162发表: 2001年 Mitochondrial DNA mutations at nucleotide 8993 show a lack of tissue- or age-re...
2.the sum total of genes transmitted from parent to offspring. Comparephenotype. [< GermanGenotypus(1909); seegene,-o-,-type] gen`o•typ′ic(-ˈtɪp ɪk)gen`o•typ′i•cal,adj. Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005,...
[ISV gene] all or part of the genetic constitution of an individual or group compare phenotype entry 1 sense 1 verb transitive verb to determine all or part of the genetic constitution of Genotyping of multiple B. pseudomallei colonies from several tissue sites from four patients … showed subst...
Background: Mutations in the high penetrance breast and ovarian cancer susceptibility gene BRCA1 account for a significant percentage of hereditary breast and ovarian cancer cases. Genotype-phenotype correlations of BRCA1 mutations located in different parts of the BRCA1 gene have been described previou...