The article discusses the role of cancer genomics in the era of precision medicine. It highlights how advancements in sequencing technology and big data analysis have made genomics a key component of cancer research, providing insights into disease etiology, risk assessment, and...
Current innovations in microscopy technology, such as the combined method ChromEMT [41], ensure its position in 3D genomics research. With the successful development of optical microscopes with a resolution of 30 nm, scientists invented a new technology-ChromEMT, by combining chromatin dyes with ele...
"We all want precision medicine, but one conclusion from these analyses is that we cannot have precision medicine without precision genomics," he explained. "Inaccurate genetic information can have substantial consequences, ranging from serious side effects related to inappropriate therapies, to a lack ...
This work was funded in part by the SMART health IT project from the Office of the National Coordinator of Health Information Technology, the Precision Link Biobank at Boston Children’s Hospital, and U01 CA231840 from the National Institutes of Health. The funders had no role in study design...
In cancer, precision medicine has been nearly synonymous with genomics. However, sobering recent studies have generally shown that most patients with cancer who receive genomic testing do not benefit from a genomic precision medicine strategy. Although some call the entire project of precision cancer ...
This is especially important in clinical cancer research, where genetic alterations in a patient's tumor may be matched to novel molecularly targeted therapies. In this review, we discuss the integration of cancer genomics and clinical oncology and the opportunity to deliver precision cancer medicine....
Precision medicine strives to delineate disease using multiple data sources—from genomics to digital health metrics—in order to be more precise and accurate in our diagnoses, definitions, and treatments of disease subtypes. By defining disease at a deeper level, we can treat patients based on an...
“This is really the first time that we’re taking medicine to an individual profile from a population profile,” Romanin says aboutprecision medicinebroadly. “So often medicine says: This is how to treat everybody who’s got metastatic renal cell carcinoma or some other disease. But the re...
Another clear example of the increasing role of imaging in precision medicine is prostate cancer [14,15]: multiparametric MRI is a potent tool for diagnosing prostate cancer and for classifying patients into subgroups with different risk levels, which helps in planning treatment and predicting ...
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