The increasing prevalence of cancer and other genetic disorders, growing preference for personalized medicine, increase in private and public sector funding, and rapid advancements in sequencing and genome editing technologies are some of the factors propelling the growth of the genome editing market. Ac...
Sampling and sequencing ofT. cordifoliagenome and transcriptome The species was confirmed asT. cordifoliawith the highest identity (98.32% for ITS and 99.41% formatK) with sequences ofT. cordifoliaavailable at NCBI (nt) database. The total genomics data generated was 102 Gb which comprised 79.4 Gb...
The human genome project was a ground-breaking scientific endeavour that not only gave us a near complete map of our genetic code but also paved the way for new innovative sequencing technologies and computational methods that have enabled the clinical application of genomics [1,2,3,4]. While ...
Reproductive success depends on the fine balance between the nutrient demand for an optimal fetal growth and the maternal nutrient requirements to support the pregnancy. This balance takes place at the feto-maternal interface, defined as the interaction between the mother (uterus/endometrium) and the...
Over the past decade, long-read, single-molecule DNA sequencing technologies have emerged as powerful players in genomics. With the ability to generate reads tens to thousands of kilobases in length with an accuracy approaching that of short-read sequencing technologies, these platforms have proven ...
sequencing survey of paired bladder and vaginal samples identified more bacterial genera within the bladder than within the vagina, suggesting a greater bacterial diversity within the urinary tract [22]. In contrast, little overlap in species was reported between the microbiota of the urinary and ...
By MedCity News “Parents can choose which groups of conditions they want to screen their baby for,” Culton said in an email. “By sequencing newborns we’re able to detect potential health problems early on so babies can receive appropriate treatment resulting in improved health outcomes.” ...
Thus, most missense variants remain as variants of uncertain significance (VUS), limiting the utility of exome sequencing in clinical diagnosis2,10. VEP is even more challenging for coding variants affecting multiple residues such as in-frame indels. Experimental approaches for VEP such as deep ...
the process of obtaining complete and accurate mitochondrial genome sequences is more intricate than that of plastomes and often requires the application of advanced sequencing technologies21. Nevertheless, complete plant mitochondrial genomes have been successfully generated using traditional short reads22,23...
and identified distinct mechano-sensing genes in the BZ of the infarct [41]. Boileau et al. introduced scNaST (single-cell nanopore spatial transcriptomics), a method targeted at the identification of RNA-isoform switches using long-read sequencing of the myocardium following infarction in different...