Specifically, we discuss the dynamics of 3D chromatin and genome organization during gametogenesis, embryonic development, lineage commitment and stem cell differentiation, and focus on the functions of chromatin architecture in transcription regulation. Finally, we discuss the role of 3D genome alterations...
Genome architecture is the arrangement of functional elements within the genome [1] and can be thought of in a linear fashion, or in the three-dimensional arrangement found in nuclei [2]. The architecture of genomes differs greatly across the tree of life. For example, bacteria tend to have ...
epigenomic, transcriptomic, and genetic variation data in pepper (C. annuum). We choose this species both because of its extensive cultivation and because its 3D chromatin architecture exhibits clear interaction domains that
Here we utilized a maize association panel including 508 inbred lines with tropical, subtropical and temperate backgrounds to decipher the genetic architecture attributed to four husk traits, i.e. number of layers, length, width and thickness. Evaluating the phenotypic diversity at two different ...
chinensehas evolved through an ancient WGD event and recent repetitive sequence bursts, leading to specific patterns of floral color and petal evolution [9]. An ancient WGD event that occurred before the radiation of most Ericaceae plants contributed to the genomic architecture of flowering time [10...
This work revealed a remarkably diverse plastic secretome. It illustrates the value of combining genome architecture with comparative genomics to identify novel candidate virulence factors from pathogen genomes. Background Phytophthora infestans, the causal agent of the potato and tomato late blight disease...
Genome architecture and tetrasomicinheritance of autotetraploid potato. Mol Plant. 2022;15(7):1211–26. https://doi.org/10.1016/j.molp.2022.06.009. Article CAS PubMed Google Scholar FAO. Statistical data. Rome. 2021. Demirel U. Environmental requirements of potato and abiotic stress factors....
Altered chromatin architecture and gene expression during polyploidization and domestication of soybean. Plant Cell. 2021;33:1430–46. Article Google Scholar Imakaev M, Fudenberg G, McCord RP, Naumova N, Goloborodko A, Lajoie BR, et al. Iterative correction of Hi-C data reveals hallmarks of ...
The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes The dynamic three-dimensional chromatin architecture of genomes and its co-evolutionary connection to its function—the storage, expression, and replicatio... TA Knoch,M...
The genome exists as an organized, three-dimensional (3D) dynamic architecture, and each cell type has a unique 3D genome organization that determines its cell identity. An unresolved question is how cell type-specific 3D genome structures are established during development. Here, we analyzed 3D ...