Also called hybrid vigour; the propensity when inbred lines of, for example, maize or domesticated animals are crossed to result in hybrids that are fitter than either parent. The trait values that were reduced by inbreeding depression increase after outbreeding. Outbreeding depression When the offs...
For example, the G2 and G3 accessions of CYP78A9-A04-Hap2 produced heavier seeds under long-day than under short-day conditions (Supplementary Fig. 29 and Supplementary Table 36). However, they showed delayed flowering under short-day environments and produced lighter seeds than the G4, G...
To get a conceptual handle on this, let’s use computer hardware (the machine) and software (instructions to the machine) as a familiar example. The genome (DNA) is the hardware (body), whereas the epigenome is the software that will tell the body what to do. The genome does the work...
For example, Scott et al. (2019) identified one QTL on Chr. 3 for resistance to P. ultimum var. ultimum and P.ultimum var. sporangiiferum, and other two QTLs (on chromosomes 13 and 17, respectively) that both confer resistance to P. irregulare and P. ultimum var. ultimum. In a ...
while idiosyncratic life experiences appear to explain a larger portion of the variation in homeownership among those who grew up in a less wealthy family environment. Furthermore, we find that home location choices, for example, a familiar home location close to one’s birthplace and an urban ...
If you cannot read the words on your pill bottle, for example, it is unlikely you will be able to follow the instructions those words attempt to convey. Furthermore, this count of 90 million does not take into account the people with average literacy skills who might also have low ...
Figure 1. An example of a case study in genetics with student prompts. A 27-year-old investment banker called his doctor concerned about malodorous urine. When the patient urinated first thing that morning, he had noticed that his urine had a terrible sulfurous smell. It was now 10:00 ...
Of note, when ordering panel-based testing, it is important to ensure that known noncoding pathogenic variants are covered, for example 5′ UTR variants in ANKRD26. Additionally, although NGS can detect small deletions, larger structural variants are missed; therefore, if those are suspected, ...
Cell-free biology is the activation of biological processes without the use of intact living cells. It has been used for more than 50 years across the life sciences as a foundational research tool, but a recent technical renaissance has facilitated high-
For example, in the ecDNA+ Group 3 primary tumor MB106, DNA interactions occurred between the MYC locus and two co-amplified accessible regions 13 Mbp away on the reference genome, but less than 1 Mbp away on the ecDNA (Fig. 4b,c). These chromatin interactions were specific to the ...