A large-scale international study involving more than 300 researchers, published today in Nature, heralds the discovery of 83 genetic variations controlling human height. To discover the 83 genetic variations, the research team measured the presence of 250,000 genetic variations in the study's 700,...
The largest genetic study of human height in an Asian population has revealed dozens of rare DNA variants specific to people of the region. The findings deepen our understanding of the complex interactions among genes that contribute to normal growth. They also highlight some of the similarities a...
Human height is a highly heritable, classic polygenic trait. Until recently, there had been limited success in identifying the specific genetic variants that explain normal variation of human height. The advent of large-scale genome-wide association studies, however, has led to dramatic progress. In...
Adult height (stature), as a complex quantitative trait, has been studied in different populations. However, few genetic studies on height were performed on the Chinese, the largest population in the world. In this study, familial correlation and segrega
Timothy Frayling, Joel Hirschhorn, Peter Visscher and colleagues report a meta-analysis of genome-wide association studies for adult height in 253,288 individuals. They identify 697 variants in 423 loci significantly associated with adult height and find
The apportionment of human genetic diversity within and between populations has been measured to understand human relatedness and demographic history. Likewise, the distribution of archaic ancestry in modern populations can be leveraged to better understand the interaction between our species and its archaic...
Tapping into natural allelic variation has always been an important means of crop enhancement. A recent study has now identified a new and powerful way of improving rice yield — by combining loci that increase grain ...
Genetics is the study of genes and the variation of characteristics that are influenced by genes—including physical and psychological characteristics. All human traits, from one's height to one's fear of heights, are driven by a complex interplay betwee
Common SNPs explain a large proportion of the heritability for human height. Nat Genet. 2010;42:565–9. https://doi.org/10.1038/ng.608. Article CAS PubMed PubMed Central Google Scholar Yang J, Lee SH, Goddard ME, Visscher PM. GCTA: a tool for genome-wide complex trait analysis. Am...
Geneticsis the study of the patterns of inheritance of specific traits. 遗传学是对特征的遗传模式的研究. 期刊摘选 His seminal research ingeneticsrevolutionized the treatment of cancer. 他在基因学上的重要研究改革了癌症的疗法. 期刊摘选 The human hologram holds a master set of keys for all humangen...