We also discuss the strong probability of finding several hundred more such loci in the near future. 展开 关键词: Humans Disease Body Height Growth and Development Quantitative Trait, Heritable Mutation Genome-Wide Association Study DOI: 10.1016/j.tig.2008.09.006 被引量: 274 ...
Earliest modern human genomes constrain timing of Neanderthal admixture Arev P. Sümer ,Hélène Rougier &Johannes Krause News|12 December 2024 Neanderthals and humans interbred more recently than scientists thought Two teams using different methods both conclude that humans and Neanderthals had children ...
About 8 per cent of affected persons have some other associated anomaly. The true value of penetrance is very probably between 23% and 40% and the penetrance falls off with 'distance' from the case. There is good reason to believe the inheritance of sex incidence in some pedigrees and for...
Genetics of obesity in humans. Endocr. Rev. 27, 710–718 (2006). Article CAS PubMed Google Scholar Saeed, S., Arslan, M. & Froguel, P. Genetics of obesity in consanguineous populations: toward precision medicine and the discovery of novel obesity genes. Obesity 26, 474–484 (2018). ...
Ischemic stroke, which accounts for 87% of cerebrovascular accidents, is responsible for massive global burden both in terms of economic cost and personal
Additionally, the F:B ratio, which can reflect obesity in humans and other mammals, was also heritable (0.15, PLRT = 0.02). Overall, these values indicate that rumen microbes are largely heritable, and that the possible effects of host genetics on the rumen core microbiota and keystone taxa...
in the genome contribute to height. We think that we can explain about 50% of the contributions to height based on genes alone. Well, what about the other 50%? Well, that probably has something to do with the environment you grew up in, ...
To our knowledge, there are no such systematic reviews dedicated to creating a catalog of host genes and genetic variants that confer susceptibility to severe viral infections in humans. Accordingly, we included different genes involved in both phases of the immune response to create a list of hum...
This technology has recently been improved in terms of the ability to analyse degraded DNA and low amounts of DNA, and has increased discrimination power. There are still some technical limitations to STR profiling, some of which can be overcome by using SNPs, which are more suitable for ...
Social science genetics is concerned with understanding whether, how and why genetic differences between human beings are linked to differences in behaviours and socioeconomic outcomes. Our review discusses the goals, methods, challenges and implications of this research endeavour. We survey how the rece...