MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain. Genes Dev. 4, 1528–1540 (1990). Article PubMed CAS Google Scholar Brivanlou, A. H. & Darnell, J. E. Signal transduction and the control of gene expression. Science 295...
致力于报道植物科学和农业科学领域最新研究进展。 Frontiers in Plant Science植物小分子多肽专刊征稿Frontiers in Plant Science植物小分子多肽专刊征稿About the journalCiteScore: 7.8Impact factor: 4.402征稿截止日期:12/16/2020征稿方向:小分子多肽前体剪切多肽识别及下游信号转导多肽的翻译后修饰多肽的长距离运输多肽信...
Vaccine genetics of IGHV1-2 VRC01-class broadly neutralizing antibody precursor naïve human B cells Jeong Hyun Lee, Laura Toy, Justin T. Kos, Yana Safonova, William R. Schief, Colin Havenar-Daughton, Corey T. Watson & Shane Crotty npj Vaccines volume 6, Article number: 113...
b, Uniform manifold approximation and projection colored by variant class and normalized energy distances (ed) between NT gRNA cells and drug-resistant cells in ABE HT-29 cells treated with the combination of dabrafenib (80 nM) and cetuximab (1 µg ml−1) for 16 h. c, Cell-...
(12), where a gain of function of IKs from a mutation in the KCNQ1 gene was found to cause familial AF. However, it has also been reported that mice with deletion of the KCNE1 protein (KCNE1−/−; complete loss of function) have spontaneous episodes of AF despite normal atrial ...
type 1 diabetes genetic susceptibility HLAbeta-cell destructiongenome screeningautoimmunityMHC CLASS-IIVITAMIN-DDISEASERISKSUSCEPTIBILITYAUTOIMMUNITYtext>Diabetes mellitus in children, adolescents and young adults results from targeted immune-mediated destruction of the pancreatic P-cells in the islets of ...
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Cell type enrichment analysis results of mouse and human developmental (dev) and adolescent and adult CNS single-cell datasets. Cell types are annotated based on the class and subclass definitions used by the mouse brain atlases. We further annotated the neurons with their respective neurotransmitter...
PARAG M TAMHANKAR, DM (Medical Genetics), MD, DNB (Paediatrics) has joined us as Senior Genetic Consultant. He carries a rich experience of more than 10 years in Medical services and research in Medical Genetics. He has won ICMR National Award for his research in Paediatrics and has several...
The large class of TDRDs play a pivotal role in the protection of germ cells against transposons [22, 23]; however, up to now their role in human spermatogenesis has not been well studied. The present study investigated the gene expression and protein levels of TDRD1, TDRD5, TDRD9 and ...