genetic testingnursingrights-based ethicsTay-Sachsvirtue ethicsSeveral genetic disorders are specific to Jewish heritage; one of the most-devastating is Tay-Sachs disease. Tay-Sachs is a fatal hereditary disease, causing progressive neurological problems for which there is no cure. Ethical issues ...
screening for Tay-Sachs and Canavan disease Alessandra Colaianni, BA, Subhashini Chandrasekharan, PhD, and Robert Cook-Deegan, MD Abstract: Genetic testing for Tay-Sachs and Canavan disease is par- ticularly important for Ashkenazi Jews, because both conditions are more frequent in that population...
Ashkenazi Jewish testing panel: Aetna considers medically necessary preconception or prenatal carrier screening for persons of Ashkenazi Jewish ancestry with a panel of genetic tests recommended by the American College of Medical Genetics (ACMG): Tay Sachs disease Canavan disease Cystic fibrosis Familial ...
Preimplantation genetic diagnosis for Tay-Sachs disease: Successful pregnancy after pre-embryo biopsy and gene amplification by polymerase chain reaction Gibbons W.E.; Gitlin S.A.; Lanzendorf S.E.; Kaufman R.A.; Slotnick R.N.; Hodgen G.D. USA Fertil Steril 1995 63/4 (723–728) DOI: ...
Tay-Sachs disease, hereditary metabolic disorder that causes progressive mental and neurologic deterioration and results in death in early childhood. The disease is inherited as an autosomal recessive trait and occurs most commonly among people of eastern European (Ashkenazic) Jewish origin. In infants ...
Genetic testing, any of a group of procedures used to identify gene variations associated with health, disease, and ancestry and to diagnose inherited diseases and disorders. A genetic test is typically issued only after a medical history, a physical exa
Genetic testing can also be performed on amniotic fluid obtained throughamniocentesis. Amniocentesis can be used to perform akaryotype, which screens for genetic disorders such as Down syndrome, cystic fibrosis, and neural tube defects like spina bifida. Side effects may include cramping, localized pai...
Tay-Sachs Disease Track 5: Biomarkers A biomarker is a biological characteristic that is objectively measured and evaluated as an indicator of normal biological or pathological processes, or a response to a therapeutic intervention. Biomarkers may be used alone or in combination to assess the health...
specific single gene. PGT-M is available for the vast majority of serious genetic conditions, as long as the particular gene mutation(s) in the family has been identified through DNA testing. Examples includecystic fibrosis,Tay-Sachs disease, aninherited cancer syndrome, or hundreds of other ...
Prospective parents or an embryo or fetus may be tested when a specific genetic disorder is suspected (e.g.,Tay-Sachsorsickle cell disease). In such a case, genetic screening begins with a complete medical history of both parents. If the parents decide to conceive or have already conceived,...