Cadherin-1 for hereditary diffuse gastric cancer: Aetna considers genetic testing for cadherin-1 (e-cadherin, CDH1) mutations for hereditary diffuse gastric cancer (DGC) is considered medically necessary when any of the following criteria is met: 2 gastric cases in a family, 1 confirmed diffuse ...
ARTICLE Impact of gene patents and licensing practices on access to genetic testing for inherited susceptibility to cancer: Comparing breast and ovarian cancers with colon cancers Robert Cook-Deegan, MD1, Christopher DeRienzo, MD, MPP2, Julia Carbone, LLB, LLM3, Subhashini Chandrasekharan, PhD1, ...
genetic counseling, and genetic testing for potentially harmful BRCA mutations in asymptomatic women with a family history of breast or ovarian cancer but no personal history of cancer or known potentially harmful BRCA mutations in their family. The USPSTF also reviewed ...
Updating the family history, especially for patients in middle-age, can shift a person into a higher risk status for various cancers and stimulate more intense screening.57 However, a 20-year retrospective study showed that a positive family history of colorectal cancer is not a strong ...
For each problem, only one of the solutions provided in the feature selection phase has been selected for testing. Accuracy and F1-score as more qualified metrics have been selected for the analysis. We remind the reader that this work does not focus on the clinical analysis but on the ...
As information about human genetics has increased rapidly in the last few years, so have genetic testing options such as newborn screening for inherited disorders, testing for genetic predispositions to certain types of cancer, and testing for genetic variations that may determine the effectiveness of...
The Hartford Courant: Cigna to require counseling before extensive genetic tests for cancer. Retrieved from https://doi.org/insurancenewsnet.com/. Google Scholar Tuckson, R. (2012). Personalized medicine: trends and prospects for the new science of genetic testing and molecular diagnostics. ...
Generally, FSLs offer germline testing for common, prevalent conditions, such as genotyping of common variants (e.g., factor V Leiden,HFEC282Y and H63D) and multigene panels for hereditary disorders that are limited to certain common diseases (e.g., breast cancer). A FSL key informant desc...
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ARTICLE Impact of gene patents and licensing practices on access to genetic testing for hereditary hemochromatosis Subhashini Chandrasekharan, PhD1, Emily Pitlick, JD2, Christopher Heaney, BA1, and Robert Cook-Deegan, MD1 Abstract: Hereditary hemochromatosis is an iron metabolism disorder that leads ...