Genetic and epigenetic trends in telomere research: a novel way in immunoepigenetics. Cell Mol Life Sci 2015;72;4095-4109.Melicher D, Buzas EI, Falus A (2015) Genetic and epigenetic trends in telomere research: a novel way in immunoepigenetics. Cell Mol Life Sci 72: 4095-4109....
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If the expression level of a gene is influenced by a genetic variant, also known as an expression QTL, then there will be differences in gene expression levels among individuals carrying different genotypes of the genetic variant. Then, if the expression level of the gene has an effect on epi...
Cancer Epigenetics Group, Molecular Pathology Program, Spanish National Cancer Centre (CNIO), Madrid, Spain 3 Department of Otolaryngology—Head and Neck Surgery, Head and Neck Cancer Research Division, Johns Hopkins University School of Medicine, Baltimore, Maryland Email: Montserrat Sanchez-Cespedes ...
R.J. Buono, in Encyclopedia of Basic Epilepsy Research, 2009 Genetic Association By contrast, genetic association analysis is performed on DNA samples from either unrelated or related individuals. One common paradigm for this type of analysis is the use of a case control study design. Unrelate...
Previous research has identified certain genes that confer a higher risk of the disease, but scientists believe there are many more genetic risk factors that have yet to be discovered. One reason why these drivers have been hard to find is that some are found in very few patients, making it...
Loddo I, Romano C (2015) Inflammatory bowel disease: genetics, epigenetics, and pathogenesis. Front Immunol 6:551. https://doi.org/10.3389/fimmu.2015.00551 Article CAS PubMed PubMed Central Google Scholar Lopez de Castro JA (2018) How ERAP1 and ERAP2 shape the peptidomes of disease-associ...
An association between AD and ApoE, CLU and CR1 locus on chromosome 1q32 (OR = 1.2) was found (Lambert et al., 2009b). These aforementioned genes (CLU, CR1 and PICALM) will clearly be the subject of intense research. Here we will discuss the main features of each of these genes, ...
base system that is faster and more accurate than three-base alignments used for bisulfite sequencing or EM-seq. The acquisition of accurate, phased genetic and epigenetic information, in a single experimental and data workflow is likely to offer numerous advantages in research and in diagnostics ...
M.C-T. was supported by the Netherlands Organization for Scientific Research and by a University of Groningen Rosalind Franklin Fellowship. Author information Authors and Affiliations Quantitative Epigenetics, European Research Institute for the Biology of Ageing, University Medical Center Groningen, ...