increases the propensity toward aggression because of reduced activation of the neural circuitry of impulse control and self-regulation. Serotonin facilitates prefrontal inhibition, and thus insufficient serotonergic activity can enhance aggression. Genetic predisposition to aggression appears to be deeply affect...
While we appreciate our limited sample size, we were unable to replicate previous findings of an association between multiethnic PRS to PCa aggression in our African population. Consequently, we call for further African-relevant whole-genome sequencing and genome-wide interrogation studies for establishin...
PRKCA is involved in cell proliferation and cell growth arrest by positive and negative regulation of cell cycle, and has an important role in learning and memory.74 PRKCA has been associated with alcoholism,75 obesity,76 memory impairment77 and predisposition to strong emotional memory.74 Reelin,...
c. Ekman d. Izard Happiness: Happiness can be defined as someone's evaluation of their life that entails several different aspects, such as satisfaction and appraisal of different moods and emotions. Answer and Explanation: The answer is option a. Lykken....
Both tryptophan hydroxylase (TPH), the rate-limiting enzyme in the synthesis of serotonin, and monoamine oxidase A (MAOA) have been implicated in impulsivity, aggression and suicidal behavior.14,15 In addition, several non-serotonergic candidate genes have been potentially associated with suicide ...
aggression81, which is known to be highly associated with suicidal behaviours82. WhileWRBhas been linked to cognitive impairment, it is unclear how it relates toself-harm behaviour. Finally, we found evidence for a suggestive association betweenSTK10andself-harm behaviour.STK10has been linked with...
Fear/anxiety and anger/aggression greatly influence health, quality of life and social interactions. They are a huge burden to wellbeing, and personal and public economics. However, while much is known about the physiology and neuroanatomy of such emotio
Genome-Wide Analysis of Genetic Predisposition to Alzheimer’s Disease and Related Sex Disparities. Alzheimer’s Res. Ther. 2019, 11, 5. [Google Scholar] [CrossRef] [Green Version] Purcell, S.; Neale, B.; Todd-Brown, K.; Thomas, L.; Ferreira, M.A.R.; Bender, D.; Maller, J.; ...
Additionally, reward deficiency can result from depleted or hereditary hypodopaminergia, which can manifest as a variety of personality traits and mental/medical disorders that have been linked to genetic studies with dopamine-depleting alleles. The carrying of known DNA antecedents, including epigenetic...
The PER3_5/5 homozygous genotype has shown a protective effect for bipolar disorder compared to the 4/4 genotype [32], and the latter has demonstrated a predisposition to higher levels of anxiety [27]. Moreover, the PER3_5/5 genotype has been associated with the presence of cognitive ...