The present invention relates generally to genetic markers for autism spectrum disorders and other childhood developmental delay disorders, in particular to copy number variant genetic markers for autism spectrum disorders.HENSEL CHARLES HENRY
et al. Autism spectrum disorders associated with X chromosome markers in French-Canadian males. Mol. Psychiatry 11, 206–213 (2006). CAS PubMed Google Scholar Fischbach, G. D. & Lord, C. The Simons Simplex Collection: a resource for identification of autism genetic risk factors. Neuron 68...
"The presence of maternal antibodies to fetal blood proteins is one of the best markers known for autism, accounting for about 12 percent of cases. In contrast, genetic factors previously identified in children with autism account for only 2 or 3 percent of cases," Campbell said. "Now we no...
A method is provided for screening subjects for genetic markers associated with autism. The method involves isolating a biological sample from a mammal and then testing for the presence of a mutated gene or a product thereof which is associated with autism. Also disclosed are isolated nucleic ...
Autism Spectrum Disorder (ASD) comprises a wide range of neuro-developmental disorders characterized by difficulties with social communication and interaction, as well as restricted and repetitive patterns of behavior, interests and activities. It has a number of symptoms including cognitive, behavioral, ...
We then tested for an association between markers coding for several catecholaminergic enzymes and autism using restriction fragment length polymorphisms. We confirmed modifications of whole-blood catecholamines, but we did not find any difference......
Autism spectrum disorder (ASD) is multifactorial and complex condition, with a marked genetic influence, as evidenced by the high heritability (around 80–90 %). Additionally, both common and rare genetic variants have an influence on the etiology and development. Several genetic syndromes are de...
Dysregulation of epigenetic processes involving histone methylation induces neurodevelopmental impairments and has been implicated in schizophrenia (SCZ) and autism spectrum disorder (ASD). Variants in the gene encoding lysine demethylase 4C (KDM4C) have been suggested to confer a risk for such disorders...
Figure 2. Autism Spectrum Disorder (ASD): Estimated Shared Environmental and Maternal Effect (2-Sided 95% CI) for Denmark, Finland, Sweden, and Nordic Countries Combined View LargeDownload All estimates are recalculated to fraction of variation explained. A indicates additive genetic effect; C, sh...
genome. We review the current knowledge of the genetic basis of POLS traits and suggest candidate genes and pathways for future studies. Pleiotropic effects may govern many of the genetic correlations, but little is still known about the mechanisms involved in trade-offs between current and future...