genetic disorderAlso found in: Thesaurus, Medical, Encyclopedia, Wikipedia. genetic disorder n. A pathological condition caused by an absent or defective gene or by a chromosomal aberration. Also called hereditary disease. American Heritage® Dictionary of the English Language, Fifth Edition. ...
Medical genetics: 3. An approach to the adult with a genetic disorder.MANY GENETIC DISORDERS DO NOT MANIFEST themselves until the adult years. Such disorders often involve multiple genetic factors interacting with multiple environmental factors, over time, to produce a phenotype. This paper reviews ...
Genetic disorders can be classified according to the way in which they develop. If the disorder is transmitted by genes inherited from only one parent, it is said to be an autosomal dominant disorder. The term autosome applies to any of the 22 chromosomes that are identical in human males an...
A medical condition that is directly caused by an abnormality in the genes. [..] + 添加翻译 英文-中文字典 基因病 UN term 遗传性疾病 CC-CEDICT 遗传病 noun At that time, very little was known about this rare genetic disorder. 那个年头,人们对这种罕见的遗传病所知不多。 Open ...
Gene Therapy is used to treat inherited Muscular disorder, cardiovascular disorder, HIV, cancer etc. In stem cell transplants, stem cells replace cells damaged by chemotherapy or disease or as a way for the donor's immune system to provoke immunity against some types of cancer and blood-related...
The genetic dissection of major depressive disorder (MDD) ranks as one of the success stories of psychiatric genetics, with genome-wide association studies (GWAS) identifying 178 genetic risk loci and proposing more than 200 candidate genes. However, the
This newpedigreeshowed an unaffected male with two grandchildren with the disorder. The two grandchildren had different mothers. This pedigree strongly suggested that the man's genes were involved, but they were not expressed until after passing through the femaleline. In this example, in the oldes...
(LCA) refers to a group of diseases that cause severe vision loss in infancy due to abnormal function and later degeneration of the retina. The first in vivo gene replacement therapy for an inherited disorder in the US, Luxturna® (voretigene neparvovec-rzyl, Spark Therapeutics), was ...
(LCA) refers to a group of diseases that cause severe vision loss in infancy due to abnormal function and later degeneration of the retina. The first in vivo gene replacement therapy for an inherited disorder in the US, Luxturna® (voretigene neparvovec-rzyl, Spark Therapeutics), was ...
M. et al. Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group. Mol. Psychiatry 26, 5124–5139 (2021). Article PubMed Google Scholar Guggenmos, M. et al. Quantitative neurobiological evidence for accelerated brain aging in alcohol dependence....