Characterization of the molecular function of the human genome and its variation across individuals is essential for identifying the cellular mechanisms that underlie human genetic traits and diseases. The Genotype-Tissue Expression (GTEx) project aims to characterize variation in gene expression levels acr...
The large population-based UK Biobank (www.ukbiobank.ac.uk), a potential natural target for exploring sex dimorphism in glycemic trait variability, did not collect fasting state samples and, therefore, could not be considered for such an analysis. Unraveling the heterogeneity in genetic effects on...
The simulation can run an algorithm that is executed in a loop. An algorithm implements the steps to be done for each iteration of the loop. The provided implementation of the genetic algorithm implements the Algorithm trait and can therefore be executed by the Simulator which is the provided ...
Currently, algorithms and softwares for genetic analysis of diploid organisms with bi-allelic markers are well-established, while those for polyploids are limited. Here, we present SHEsisPlus, the online algorithm toolset for both dichotomous and quantitative trait genetic analysis on polyploid species ...
Tuber bruising in tetraploid potatoes (Solanum tuberosum) is a trait of economic importance, as it affects tubers’ fitness for sale. Understanding the genetic components affecting tuber bruising is a key step in developing potato lines with increased re
Short communication: Reliability of single-step genomic BLUP breeding values by multi-trait test-day model analysis - ScienceDirect The purpose of our study was to develop an approximation procedure to estimate reliabilities of single-step genomic BLUP breeding values in a test-day mode... J Bauer...
in the determination of the yellow color trait of the YFCs. From the selection sweep analysis, it was not a surprise to detect a strong selection for the BCDO2 gene and a common genetic architecture of the gene among all the YFCs. Even the HB chickens which are phylogenetically and geograph...
They code for an RNA-dependent RNA polymerase (RDR) belonging to the RDRγ type defined by a DFDGD catalytic domain. In this study, we first fine-mapped the TYLCV resistance in S. chilense LA1932, LA1960 and LA1971. Results showed that chromosomal intervals of the causal genes in these ...
(BMI) is the most commonly studied body composition phenotype and its associated genetic variants have been found to be significantly overrepresented in genes and genomic regions active in brain cell types22, suggesting it may be a partially behavioural trait. Several studies have also shown negative...
Most existing tools for constructing genetic prediction models begin with the assumption that all genetic variants contribute equally towards the phenotype. However, this represents a suboptimal model for how heritability is distributed across the genome